Fostamatinib disodium hexahydrate
Tier C — Watch / tradeFostamatinib disodium hexahydrate
Targets：Syk
Brand：タバリス, Tavalisse, Tavlesse
Indications (approved)：Immune thrombocytopenic purpura, Thrombocytopenia
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| FOST-001 | 575484-83-2Available | 6-[(2-chloro-5-fluoropyrimidin-4-yl)amino]-2,2-dimethyl-4H-pyrido[3,2-b][1,4]oxazin-3-one |
| FOST-002 | 24313-88-0Available | 3,4,5-trimethoxyaniline |
| FOST-003 | 841290-80-0Available | 6-((5-fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one |
| FOST-004 | 229625-50-7Available | di-tert-butyl (chloromethyl) phosphate |
| FOST-005 | 901119-38-8Available | di-tert-butyl ((6-((5-fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-3-oxo-2H-pyrido[3,2-b][1,4]oxazin-4(3H)-yl)methyl) phosphate |
| FOST-006 | 901119-35-5Available | (6-((5-fluoro-2-((3,4,5-trimethoxyphenyl)amino)pyrimidin-4-yl)amino)-2,2-dimethyl-3-oxo-2H-pyrido[3,2-b][1,4]oxazin-4(3H)-yl)methyl dihydrogen phosphate |
Frequently asked questions
What are the approved indications of Fostamatinib disodium hexahydrate?
Approved indications include: Immune thrombocytopenic purpura, Thrombocytopenia.
When does the Fostamatinib disodium hexahydrate patent expire?
No public expiry year is available for Fostamatinib disodium hexahydrate yet; this page updates once verified.
How many synthesis routes are recorded for Fostamatinib disodium hexahydrate?
1 synthesis routes are recorded; the shortest is 4 steps with 8.18 total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Fostamatinib disodium hexahydrate intermediates?
6 intermediate CAS of Fostamatinib disodium hexahydrate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Fostamatinib disodium hexahydrate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29