Etrumadenant
Tier C — Watch / tradeEtrumadenant
Targets：ADORA2B, ADORA2A
Indications (approved)：胰腺导管癌, Urothelial carcinoma, Metastatic cancer, Non-small cell lung cancer, Lung cancer, Rectal cancer, Prostate cancer, Colorectal cancer
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| AB-928-001 | 56-05-3 | 4,6-dichloropyrimidin-2-amine |
| AB-928-002 | 1231892-37-7 | 2-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile |
| AB-928-003 | 2239278-05-6 | 3-(2-amino-6-chloropyrimidin-4-yl)-2-methylbenzonitrile |
| AB-928-004 | 89343-06-6Available | ethynyltriisopropylsilane |
| AB-928-005 | 2239278-06-7 | 3-(2-amino-6-((triisopropylsilyl)ethynyl)pyrimidin-4-yl)-2-methylbenzonitrile |
| AB-928-006 | 2239277-63-3 | 3-(2-amino-6-ethynylpyrimidin-4-yl)-2-methylbenzonitrile |
| AB-928-007 | 1202403-01-7 | 2-(6-(azidomethyl)pyridin-2-yl)propan-2-ol |
| AB-928-008 | 39977-44-1 | methyl 6-(hydroxymethyl)picolinate |
| AB-928-009 | 933791-33-4 | 2-(6-(hydroxymethyl)pyridin-2-yl)propan-2-ol |
Frequently asked questions
What are the approved indications of Etrumadenant?
Approved indications include: 胰腺导管癌, Urothelial carcinoma, Metastatic cancer, Non-small cell lung cancer, Lung cancer, Rectal cancer, Prostate cancer, Colorectal cancer.
When does the Etrumadenant patent expire?
No public expiry year is available for Etrumadenant yet; this page updates once verified.
How many synthesis routes are recorded for Etrumadenant?
1 synthesis routes are recorded; the shortest is 6 steps with 6.08 g (AB-928) total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Etrumadenant intermediates?
1 intermediate CAS of Etrumadenant are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Etrumadenant intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-07