Milciclib maleate
Tier C — Watch / tradeMilciclib maleate
Targets：Trk-A, CDK2
Indications (approved)：Non-small cell lung cancer, 胸腺瘤, Hepatocellular carcinoma, Solid tumour
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| PHA-848125-007 | 802541-49-7 | (Z)-ethyl 6-((dimethylamino)methylene)-1,4,4-trimethyl-7-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxylate |
| PHA-848125-008 | 50-01-1 | guanidine hydrochloride |
| PHA-848125-009 | 802534-92-5 | ethyl 8-amino-1,4,4-trimethyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylate |
| PHA-848125-010 | 110-46-3Available | isopentyl nitrite |
| PHA-848125-011 | 802535-78-0 | ethyl 8-iodo-1,4,4-trimethyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylate |
| PHA-848125-012 | - | 8-iodo-1,4,4-trimethyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxylic acid |
| PHA-848125-001 | 126-81-8 | 5,5-dimethylcyclohexane-1,3-dione |
| PHA-848125-002 | 4683-45-8 | 3-methoxy-5,5-dimethylcyclohex-2-enone |
| PHA-848125-003 | 17421-93-1 | 4,4-dimethyl-7-oxabicyclo[4.1.0]heptan-2-one |
| PHA-848125-004 | 85312-29-4 | 2-methoxy-5,5-dimethylcyclohex-2-enone |
| PHA-848125-005 | 802541-48-6 | ethyl 1,4,4-trimethyl-7-oxo-4,5,6,7-tetrahydro-1H-indazole-3-carboxylate |
| PHA-848125-006 | 36805-97-7 | 1,1-di-tert-butoxy-N,N-dimethylmethanamine |
| PHA-848125-013 | 802540-46-1 | 8-iodo-N,1,4,4-tetramethyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide |
| PHA-848125-014 | 16153-81-4 | 4-(4-methylpiperazin-1-yl)aniline |
Frequently asked questions
What are the approved indications of Milciclib maleate?
Approved indications include: Non-small cell lung cancer, 胸腺瘤, Hepatocellular carcinoma, Solid tumour.
When does the Milciclib maleate patent expire?
No public expiry year is available for Milciclib maleate yet; this page updates once verified.
How many synthesis routes are recorded for Milciclib maleate?
1 synthesis routes are recorded; the shortest is 10 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Milciclib maleate intermediates?
1 intermediate CAS of Milciclib maleate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Milciclib maleate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-21