Vorolanib
Tier C — Watch / tradeVorolanib
Targets：VEGFR2, KIT, PDGFR, FLT3, RET, JAK1
Brand：DURAVYU™
Indications (approved)：Renal cell carcinoma
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| VORO-001 | 56341-41-4Available | 5-fluoroindolin-2-one |
| VORO-002 | 253870-02-9Available | 5-formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid |
| VORO-003 | 356068-93-4 | (Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid |
| VORO-004 | 452105-55-4 | 3H-[1,2,3]triazolo[4,5-b]pyridin-3-yl (Z)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxylate |
| VORO-005 | 1568179-08-7 | (S)-3-amino-N,N-dimethylpyrrolidine-1-carboxamide |
| Vorolanib | 1013920-15-4 | (S,Z)-N-(1-(dimethylcarbamoyl)pyrrolidin-3-yl)-5-((5-fluoro-2-oxoindolin-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-carboxamide |
Frequently asked questions
What are the approved indications of Vorolanib?
Approved indications include: Renal cell carcinoma.
When does the Vorolanib patent expire?
No public expiry year is available for Vorolanib yet; this page updates once verified.
How many synthesis routes are recorded for Vorolanib?
1 synthesis routes are recorded; the shortest is 3 steps with 20 mg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Vorolanib intermediates?
2 intermediate CAS of Vorolanib are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Vorolanib intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29