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Formoterol Fumarate

Tier C — Watch / trade

Formoterol Fumarate

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Originator
-
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets：ADRB2

Brand：Eolus, Atimos, Oxeze, Oxis, Broncoral, Foradil Aerolizer, Foradil, Foradil Certihaler, Oxis Turbuhaler, Atock, Perforomist

Indications (approved)：Chronic obstructive pulmonary disease, Emphysema, Asthma, Bronchitis

Regional status

US
Phase II
2002-07-01
EU
Approved
1996-10-14
China
Approved
2000-02-03
Japan
Approved
2012-06-29

Factories producing this API3

Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.

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Synthetic routes & intermediates6 routes

Originator routes × 0Optimised (non-patent) × 6Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OptimisedRoute 1Steps 8 · Total yield 500mg(Formoterol Fumarate (API))
Formoterol Fumarate-001—Formoterol Fumarate-002—Formoterol Fumarate-003—Formoterol Fumarate-004—Formoterol Fumarate-0051199228-78-8Formoterol Fumarate-006—Formoterol Fumarate-007—Formoterol Fumarate-008—Formoterol Fumarate-009—Formoterol Fumarate-010—Formoterol Fumarate-011—Formoterol Fumarate-012—API · Formoterol Fumarate
CodeCAS No.Intermediate
Formoterol Fumarate-001-1-(4-Hydroxy-3-nitrophenyl)ethan-1-one
Formoterol Fumarate-002-1-(4-(Benzyloxy)-3-nitrophenyl)ethanone
Formoterol Fumarate-003-1-(4-(Benzyloxy)-3-nitrophenyl)-2-bromoethanone
Formoterol Fumarate-004-(2R*)-N-Benzyl-1-(4-methoxyphenyl)propan-2-amine
Formoterol Fumarate-0051199228-78-8(2R)-N-Benzyl-1-(4-methoxyphenyl)propan-2-amine hydrogen chloride
Formoterol Fumarate-006-2-[Benzyl[(2R*)-1-(4-methoxyphenyl)propan-2-yl]amino]-1-[4-(benzyloxy)-3-nitrophenyl]ethanone
Formoterol Fumarate-007-(1R*)-2-[Benzyl[(2R*)-1-(4-methoxyphenyl)propan-2-yl]amino]-1-[4-(benzyloxy)-3-nitrophenyl]ethanol
Formoterol Fumarate-008-(1R*)-1-[3-Amino-4-(benzyloxy)phenyl]-2-[benzyl[(2R*)-1-(4-methoxyphenyl)propan-2-yl]amino]ethanol
Formoterol Fumarate-009-Acido formico
Formoterol Fumarate-010-Amide c1
Formoterol Fumarate-011-N-[5-[(1R*)-2-[Benzyl[(2R*)-1-(4-methoxyphenyl)propan-2-yl]amino]-1-hydroxyethyl]-2-(benzyloxy)phenyl]formamide
Formoterol Fumarate-012-N-[2-Hydroxy-5-[1(R*)-hydroxy-2-[1(R*)-methyl-2-(4-methoxyphenyl)ethylamino]ethyl]phenyl]formamide
OptimisedRoute 2Steps 1 · Total yield /
Formoterol Fumarate-013960303-94-0Formoterol Fumarate-014—Formoterol Fumarate-015—API · Formoterol Fumarate
CodeCAS No.Intermediate
Formoterol Fumarate-013960303-94-0N-{5-[(1R)-2-amino-1-hydroxyethyl]-2-hydroxyphenyl}formamide
Formoterol Fumarate-014-1-(4-Methoxyphenyl)-2-propanone
Formoterol Fumarate-015-1,2-Ethylenedicarboxylic acid
OptimisedRoute 3Steps 1 · Total yield 150mg(Formoterol Fumarate-017)
Formoterol Fumarate-016345288-55-3Formoterol Fumarate-017126587-93-7API · Formoterol Fumarate
CodeCAS No.Intermediate
Formoterol Fumarate-016345288-55-31-[4-(Benzyloxy)-3-nitrophenyl]-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethanol
Formoterol Fumarate-017126587-93-7N-[2-(Benzyloxy)-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]formamide
OptimisedRoute 4Steps 8 · Total yield 3.84g(Formoterol Fumarate (API))
Formoterol Fumarate-01843229-66-9Formoterol Fumarate-01943229-67-0Formoterol Fumarate-020—Formoterol Fumarate-021—Formoterol Fumarate-008—Formoterol Fumarate-007—Formoterol Fumarate-009—Formoterol Fumarate-011—Formoterol Fumarate-012—API · Formoterol Fumarate
CodeCAS No.Intermediate
Formoterol Fumarate-01843229-66-92-[Benzyl[1-(4-methoxyphenyl)propan-2-yl]amino]-1-[4-(benzyloxy)-3-nitrophenyl]ethanone
Formoterol Fumarate-01943229-67-02-[Benzyl[1-(4-methoxyphenyl)propan-2-yl]amino]-1-[4-(benzyloxy)-3-nitrophenyl]ethanol
Formoterol Fumarate-020-1-(4-Methoxyphenyl)-2-benzylaminopropane
Formoterol Fumarate-021-2-[4-(Benzyloxy)-3-nitrophenyl]oxirane
Formoterol Fumarate-008-(1R*)-1-[3-Amino-4-(benzyloxy)phenyl]-2-[benzyl[(2R*)-1-(4-methoxyphenyl)propan-2-yl]amino]ethanol
Formoterol Fumarate-007-(1R*)-2-[Benzyl[(2R*)-1-(4-methoxyphenyl)propan-2-yl]amino]-1-[4-(benzyloxy)-3-nitrophenyl]ethanol
Formoterol Fumarate-009-Acido formico
Formoterol Fumarate-011-N-[5-[(1R*)-2-[Benzyl[(2R*)-1-(4-methoxyphenyl)propan-2-yl]amino]-1-hydroxyethyl]-2-(benzyloxy)phenyl]formamide
Formoterol Fumarate-012-N-[2-Hydroxy-5-[1(R*)-hydroxy-2-[1(R*)-methyl-2-(4-methoxyphenyl)ethylamino]ethyl]phenyl]formamide
OptimisedRoute 5Steps 3 · Total yield /
Formoterol Fumarate-022—Formoterol Fumarate-023—Formoterol Fumarate-024—Formoterol Fumarate-025—API · Formoterol Fumarate
CodeCAS No.Intermediate
Formoterol Fumarate-022--
Formoterol Fumarate-023--
Formoterol Fumarate-024--
Formoterol Fumarate-025--
OptimisedRoute 6Steps 1 · Total yield /
Formoterol Fumarate-026—Formoterol Fumarate-027—API · Formoterol Fumarate
CodeCAS No.Intermediate
Formoterol Fumarate-026-Anisole
Formoterol Fumarate-027-1-Chloro-4-methoxybenzene

Frequently asked questions

What are the approved indications of Formoterol Fumarate?

Approved indications include: Chronic obstructive pulmonary disease, Emphysema, Asthma, Bronchitis.

When does the Formoterol Fumarate patent expire?

No public expiry year is available for Formoterol Fumarate yet; this page updates once verified.

How many synthesis routes are recorded for Formoterol Fumarate?

6 synthesis routes are recorded; the shortest is 1 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Formoterol Fumarate intermediates?

All intermediates in Formoterol Fumarate routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Formoterol Fumarate intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29