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Fezolinetant

Tier C — Watch / trade

Fezolinetant

Ogeda SA
Originator
2023
First approval
-
Expiry (public)
$0.31B ▲
Peak sales
Small molecule
Type

Targets:NK3R

Brand:VEOZAH

Indications (approved):Vasomotor symptoms, Hot flushes

Regional status

US
Approved
2023-05-12
EU
Approved
2023-12-07
China
Phase III
2020-03-17
Japan
Phase III
2024-02-16

Factories producing this API1

Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.

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Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 3 · Total yield 0.795 g
FEZO-0011383146-20-0FEZO-0021429560-52-0FEZO-0031375066-73-1FEZO-0041429558-08-6FEZO-005403-43-0API · Fezolinetant
CodeCAS No.Intermediate
FEZO-0011383146-20-0Available(R)-4-(2,4-dimethoxybenzyl)-3-methylpiperazin-2-one
FEZO-0021429560-52-0Available(R)-1-(2,4-dimethoxybenzyl)-5-ethoxy-6-methyl-1,2,3,6-tetrahydropyrazine
FEZO-0031375066-73-1Available3-methyl-1,2,4-thiadiazole-5-carbohydrazide
FEZO-0041429558-08-6Available(R)-3-methyl-5-(8-methyl-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)-1,2,4-thiadiazole
FEZO-005403-43-0Available4-fluorobenzoyl chloride

Frequently asked questions

What are the approved indications of Fezolinetant?

Approved indications include: Vasomotor symptoms, Hot flushes.

When does the Fezolinetant patent expire?

No public expiry year is available for Fezolinetant yet; this page updates once verified.

How many synthesis routes are recorded for Fezolinetant?

1 synthesis routes are recorded; the shortest is 3 steps with 0.795 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Fezolinetant intermediates?

5 intermediate CAS of Fezolinetant are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Fezolinetant intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29