Miconazole/Metronidazole/Lidocaine

Tier C — Watch / trade

Exeltis

Originator

2010

First approval

Expiry (public)

No sales data

Peak sales

Small molecule

Type

Targets：CYP51A1, Sodium channels

Brand：Neo-Penotran Forte L

Indications (approved)：Trichomoniasis, Candidiasis, Vaginitis

Regional status

China

Discontinued

2008-06-13

Japan

Factories producing this API13

Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.

13 producing factories on file — sign in to view the named list (factory details are not shown to guests).

Synthetic routes & intermediates5 routes

Originator routes × 0Optimised (non-patent) × 3Process routes × 2

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OptimisedRoute 3Steps 2 · Total yield /

Lidocaine Hydrochloride-023—Lidocaine Hydrochloride-024—Lidocaine Hydrochloride-025—Lidocaine Hydrochloride-010—API · Miconazole/Metronidazole/Lidocaine

Code	CAS No.	Intermediate
Lidocaine Hydrochloride-023	-	N-Formyldiethylamine
Lidocaine Hydrochloride-024	-	N-Ethyl-N-[(tributylstannyl)methyl]ethanamine
Lidocaine Hydrochloride-025	-	2-Isocyanato-1,3-dimethylbenzene
Lidocaine Hydrochloride-010	-	2-Diethylamino-N-(2,6-dimethylphenyl)acetamide

OptimisedRoute 1Steps 6 · Total yield 8.5g(Metronidazole (Free))

Metronidazole hydrochloride-001107-22-2Metronidazole hydrochloride-00275-07-0Metronidazole hydrochloride-003693-98-1Metronidazole hydrochloride-004696-23-1Metronidazole hydrochloride-005107-07-3Metronidazole hydrochloride-00675-05-8Metronidazole hydrochloride-007—Metronidazole hydrochloride-00822483-09-6Metronidazole hydrochloride-009—API · Miconazole/Metronidazole/Lidocaine

Code	CAS No.	Intermediate
Metronidazole hydrochloride-001	107-22-2 Available	Glyoxal
Metronidazole hydrochloride-002	75-07-0	Ethanal
Metronidazole hydrochloride-003	693-98-1	2-Methylglyoxaline
Metronidazole hydrochloride-004	696-23-1	2-Methyl-4(5)-nitroimidazole
Metronidazole hydrochloride-005	107-07-3	Ethylene chlorohydrin
Metronidazole hydrochloride-006	75-05-8	Ethyl nitrile
Metronidazole hydrochloride-007	-	Methyl ethanimidoate hydrochloride
Metronidazole hydrochloride-008	22483-09-6	2,2-Dimethoxyethanamine
Metronidazole hydrochloride-009	-	N-(2,2-Dimethoxyethyl)ethanimidamide

OptimisedRoute 1Steps 1 · Total yield 34 g

MICO-00113692-14-3MICO-00294-99-5MICO-003288-32-4Miconazole Nitrate22916-47-8API · Miconazole/Metronidazole/Lidocaine

Code	CAS No.	Intermediate
MICO-001	13692-14-3	2-chloro-1-(2,4-dichlorophenyl)ethan-1-ol
MICO-002	94-99-5	2,4-dichloro-1-(chloromethyl)benzene
MICO-003	288-32-4	1H-imidazole
Miconazole Nitrate	22916-47-8	1-(2-((2,4-dichlorobenzyl)oxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole

ProcessRoute 1Steps 8 · Total yield 93.4kg(Lidocaine Hydrochloride (API))

Lidocaine Hydrochloride-001—Lidocaine Hydrochloride-002—Lidocaine Hydrochloride-003—Lidocaine Hydrochloride-004—Lidocaine Hydrochloride-005—Lidocaine Hydrochloride-006—Lidocaine Hydrochloride-007—Lidocaine Hydrochloride-008—Lidocaine Hydrochloride-009—Lidocaine Hydrochloride-010—Lidocaine Hydrochloride-011—Lidocaine Hydrochloride-01259858-41-2Lidocaine Hydrochloride-013—Lidocaine Hydrochloride-014—Lidocaine Hydrochloride-015—Lidocaine Hydrochloride-016—Lidocaine Hydrochloride-017—API · Miconazole/Metronidazole/Lidocaine

Code	CAS No.	Intermediate
Lidocaine Hydrochloride-001	-	1,3-Dimethyl-2-nitrobenzene
Lidocaine Hydrochloride-002	-	2-Amino-1,3-dimethylbenzene
Lidocaine Hydrochloride-003	-	2-Bromanylethanoic acid
Lidocaine Hydrochloride-004	-	2-Chloroacetic acid
Lidocaine Hydrochloride-005	-	2-Chloranylethanoyl chloride
Lidocaine Hydrochloride-006	-	2-Chloroacetic acid methyl ester
Lidocaine Hydrochloride-007	-	2-Bromo-N-(2,6-dimethylphenyl)acetamide
Lidocaine Hydrochloride-008	-	1-Chloroacetylamino-2,6-dimethylbenzene
Lidocaine Hydrochloride-009	-	N-Ethylethanamine
Lidocaine Hydrochloride-010	-	2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
Lidocaine Hydrochloride-011	-	2-(Diethylamino)acetic acid
Lidocaine Hydrochloride-012	59858-41-2	2-(Diethylamino)acetyl chloride
Lidocaine Hydrochloride-013	-	Methyl 2-(diethylamino)acetate
Lidocaine Hydrochloride-014	-	3-(2-Methoxyphenyl)-1H-pyrazole
Lidocaine Hydrochloride-015	-	2-(Chloromethyl)pyridine hydrochloride
Lidocaine Hydrochloride-016	-	-
Lidocaine Hydrochloride-017	-	Dichloridomanganese 2-[[3-(2-methoxyphenyl)-1H-pyrazol-1-yl]methyl]pyridine

ProcessRoute 2Steps 2 · Total yield 441.0666g(Lidocaine (Free))

Lidocaine Hydrochloride-002—Lidocaine Hydrochloride-01844978-98-5Lidocaine Hydrochloride-01927794-54-3Lidocaine Hydrochloride-020134756-56-2Lidocaine Hydrochloride-0211546682-40-9Lidocaine Hydrochloride-010—Lidocaine Hydrochloride-009—Lidocaine Hydrochloride-022—API · Miconazole/Metronidazole/Lidocaine

Code	CAS No.	Intermediate
Lidocaine Hydrochloride-002	-	2-Amino-1,3-dimethylbenzene
Lidocaine Hydrochloride-018	44978-98-5	N2,N2-Diethyl-N,N-dimethylglycinamide
Lidocaine Hydrochloride-019	27794-54-3	N,N,N2,N2-Tetraethylglycinamide
Lidocaine Hydrochloride-020	134756-56-2	N2,N2-Diethyl-N,N-dipropan-2-ylglycinamide
Lidocaine Hydrochloride-021	1546682-40-9	N2,N2-Diethyl-N,N-dipropylglycinamide
Lidocaine Hydrochloride-010	-	2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
Lidocaine Hydrochloride-009	-	N-Ethylethanamine
Lidocaine Hydrochloride-022	-	N-(2,6-Dimethylphenyl)-2-hydroxyacetamide

Frequently asked questions

What are the approved indications of Miconazole/Metronidazole/Lidocaine?

Approved indications include: Trichomoniasis, Candidiasis, Vaginitis.

When does the Miconazole/Metronidazole/Lidocaine patent expire?

No public expiry year is available for Miconazole/Metronidazole/Lidocaine yet; this page updates once verified.

How many synthesis routes are recorded for Miconazole/Metronidazole/Lidocaine?

5 synthesis routes are recorded; the shortest is 1 steps with 34 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Miconazole/Metronidazole/Lidocaine intermediates?

1 intermediate CAS of Miconazole/Metronidazole/Lidocaine are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Miconazole/Metronidazole/Lidocaine intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29