Unibest
← Back to patent-cliff list

Omeprazole

Tier C — Watch / trade

Omeprazole

-
Originator
1991
First approval
-
Expiry (public)
$0.95B ▲
Peak sales
Small molecule
Type

Targets:Proton pump

Brand:Nuclosina, Omepral, Parizac, Omeprazon, Emilok, Audazol, Losec, Prilosec, Antra, Omeprazone, Losec/Prilosec, Omapren, Omez, Omepradex, Mopral, Miol

Indications (approved):Heartburn, Gastro-oesophageal reflux disease, Gastric ulcer, Hyperacidity, Duodenal ulcer, Helicobacter pylori infection

Regional status

US
Approved
2009-04-02
EU
-
China
Approved
1992-01-01
Japan
Approved
1991-04-01

Factories producing this API1

Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.

1 producing factories on file — sign in to view the named list (factory details are not shown to guests).

Sign in to view factories →

Synthetic routes & intermediates3 routes

Originator routes × 0Optimised (non-patent) × 3Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OptimisedRoute 1Steps 3 · Total yield /
OMEP-00186604-78-6OMEP-00286604-75-3OMEP-00337052-78-1OMEP-00473590-85-9OMEP-005937-14-4Omeprazole73590-58-6API · Omeprazole
CodeCAS No.Intermediate
OMEP-00186604-78-6(4-methoxy-3,5-dimethylpyridin-2-yl)methanol
OMEP-00286604-75-35-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)thio)-1H-imidazo[4,5-b]pyridine
OMEP-00337052-78-15-methoxy-1H-benzo[d]imidazole-2-thiol
OMEP-00473590-85-95-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole
OMEP-005937-14-43-chlorobenzoperoxoic acid
Omeprazole73590-58-6-
OptimisedRoute 2Steps 1 · Total yield 10 mg (Omeprazole)
OMEP-006142885-92-5API · Omeprazole
CodeCAS No.Intermediate
OMEP-006142885-92-54-methoxy-2-(((5-methoxy-1H-benzo[d]imidazol-2-yl)thio)methyl)-3,5-dimethylpyridine 1-oxide
OptimisedRoute 3Steps 3 · Total yield /
OMEP-00337052-78-1OMEP-0071080503-55-4OMEP-008—OMEP-009109371-19-9API · Omeprazole
CodeCAS No.Intermediate
OMEP-00337052-78-15-methoxy-1H-benzo[d]imidazole-2-thiol
OMEP-0071080503-55-4sodium 5-methoxy-2-sulfinatobenzo[d]imidazol-1-ide
OMEP-008-A name could not be generated for this structure. 系统无法命名
OMEP-009109371-19-94-methoxy-2,3,5-trimethylpyridine

Frequently asked questions

What are the approved indications of Omeprazole?

Approved indications include: Heartburn, Gastro-oesophageal reflux disease, Gastric ulcer, Hyperacidity, Duodenal ulcer, Helicobacter pylori infection.

When does the Omeprazole patent expire?

No public expiry year is available for Omeprazole yet; this page updates once verified.

How many synthesis routes are recorded for Omeprazole?

3 synthesis routes are recorded; the shortest is 1 steps with 10 mg (Omeprazole) total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Omeprazole intermediates?

All intermediates in Omeprazole routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Omeprazole intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29