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Elexacaftor/ivacaftor/tezacaftor

Tier B — Position early

Elexacaftor/ivacaftor/tezacaftor

Vertex Pharmaceuticals Incorporated
Originator
2019
First approval
-
Expiry (public)
$10.31B ▲
Peak sales
Small molecule
Type

Targets:CFTR, PGY1

Brand:TRIKAFTA, Trikafta, Kaftrio

Indications (approved):Cystic fibrosis

Regional status

US
Approved
2019-10-21
EU
Approved
2020-08-21
China
-
Japan
-

Synthetic routes & intermediates

Routes not yet onboarded — the daily pipeline enriches by priority (approved small molecules first); this page updates automatically.

Frequently asked questions

What are the approved indications of Elexacaftor/ivacaftor/tezacaftor?

Approved indications include: Cystic fibrosis.

When does the Elexacaftor/ivacaftor/tezacaftor patent expire?

No public expiry year is available for Elexacaftor/ivacaftor/tezacaftor yet; this page updates once verified.

How do I get a quote for Elexacaftor/ivacaftor/tezacaftor intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29