Amrubicin Hydrochloride
Tier C — Watch / tradeAmrubicin Hydrochloride
Targets：TOP2
Brand：Amrubicin, Calsed
Indications (approved)：Non-small cell lung cancer, Small cell lung cancer
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| AMRU-001 | 37464-90-7 | 5,8-dimethoxy-3,4-dihydronaphthalen-2(1H)-one |
| AMRU-002 | 99907-84-3 | 2-amino-5,8-dimethoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid |
| AMRU-003 | - | methyl (R)-2-amino-5,8-dimethoxy-1,2,3,4-tetrahydronaphthalene-2-carboxylate |
| AMRU-004 | 110267-86-2 | (R)-1-(2-amino-5,8-dimethoxy-1,2,3,4-tetrahydronaphthalen-2-yl)ethan-1-one |
| AMRU-005 | 86264-61-1 | (R)-N-(2-acetyl-5,8-dimethoxy-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide |
| AMRU-006 | 85-44-9Available | isobenzofuran-1,3-dione |
| AMRU-007 | 104319-02-0 | (R)-N-(2-acetyl-5,12-dihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)acetamide |
| AMRU-008 | 86264-76-8 | (R)-N-(5,12-dihydroxy-2-(2-methyl-1,3-dioxolan-2-yl)-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)acetamide |
| AMRU-009 | 110267-78-2 | (1S,5S)-7,14-dihydroxy-3-methyl-5-(2-methyl-1,3-dioxolan-2-yl)-5,6-dihydro-1H-1,5-methanoanthra[2,3-f][1,3]oxazocine-8,13-dione |
| AMRU-010 | 92395-41-0 | (7S,9S)-9-acetyl-9-amino-6,7,11-trihydroxy-7,8,9,10-tetrahydrotetracene-5,12-dione |
| AMRU-011 | - | - |
| AMRU-012 | - | - |
Frequently asked questions
What are the approved indications of Amrubicin Hydrochloride?
Approved indications include: Non-small cell lung cancer, Small cell lung cancer.
When does the Amrubicin Hydrochloride patent expire?
No public expiry year is available for Amrubicin Hydrochloride yet; this page updates once verified.
How many synthesis routes are recorded for Amrubicin Hydrochloride?
1 synthesis routes are recorded; the shortest is 10 steps with 1.12 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Amrubicin Hydrochloride intermediates?
1 intermediate CAS of Amrubicin Hydrochloride are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Amrubicin Hydrochloride intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29