Dactolisib
Tier C — Watch / tradeDactolisib
Targets：mTORC1, mTORC2, PI3Kβ, PI3Kα, PI3Kγ, PI3Kδ
Indications (approved)：COVID-19, Respiratory tract infection, Breast cancer, 呼吸障碍, Solid tumour, Pancreatic neuroendocrine tumour, 肾肿瘤, Urothelial carcinoma
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| DACT-001 | 555-21-5 | 2-(4-nitrophenyl)acetonitrile |
| DACT-002 | 71825-51-9 | 2-methyl-2-(4-nitrophenyl)propanenitrile |
| DACT-003 | 115279-57-7 | 2-(4-aminophenyl)-2-methylpropanenitrile |
| DACT-004 | 723281-72-9 | 6-bromo-4-chloro-3-nitroquinoline |
| DACT-005 | 915019-51-1 | 2-(4-((6-bromo-3-nitroquinolin-4-yl)amino)phenyl)-2-methylpropanenitrile |
| DACT-006 | 915019-52-2 | 2-(4-((3-amino-6-bromoquinolin-4-yl)amino)phenyl)-2-methylpropanenitrile |
| DACT-007 | 915019-53-3 | 2-(4-(8-bromo-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl)phenyl)-2-methylpropanenitrile |
| DACT-008 | 915019-50-0 | 2-(4-(8-bromo-3-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-c]quinolin-1-yl)phenyl)-2-methylpropanenitrile |
| DACT-009 | 191162-39-7 | quinolin-3-ylboronic acid |
| DACT-010 | 5794-88-7 | 2-amino-5-bromobenzoic acid |
| DACT-011 | 1201643-75-5 | (E)-5-bromo-2-((2-nitrovinyl)amino)benzoic acid |
| DACT-012 | 853908-50-6 | 6-bromo-3-nitroquinolin-4-ol |
Frequently asked questions
What are the approved indications of Dactolisib?
Approved indications include: COVID-19, Respiratory tract infection, Breast cancer, 呼吸障碍, Solid tumour, Pancreatic neuroendocrine tumour, 肾肿瘤, Urothelial carcinoma.
When does the Dactolisib patent expire?
No public expiry year is available for Dactolisib yet; this page updates once verified.
How many synthesis routes are recorded for Dactolisib?
1 synthesis routes are recorded; the shortest is 10 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Dactolisib intermediates?
All intermediates in Dactolisib routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Dactolisib intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-19