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AQW-051

Tier C — Watch / trade

AQW-051

Novartis
Originator
-
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:nAChRα7

Indications (approved):Anxiety, 表现焦虑, Alzheimer's disease, Mild cognitive impairment, Schizophrenia, 运动障碍

Regional status

US
Phase III
2025-09-22
EU
Discontinued
2007-12-01
China
-
Japan
No progress
2006-10-01

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 3 · Total yield /
AQW-051669770-29-0AQW-051-0011072-98-6AQW-051-00240473-01-6AQW-051-0035720-05-8AQW-051-004669770-63-2AQW-051-00525333-42-0API · AQW-051
CodeCAS No.Intermediate
AQW-051669770-29-0-
AQW-051-0011072-98-65-chloropyridin-2-amine
AQW-051-00240473-01-62-bromo-5-chloropyridine
AQW-051-0035720-05-8p-tolylboronic acid
AQW-051-004669770-63-25-chloro-2-(p-tolyl)pyridine
AQW-051-00525333-42-0(R)-quinuclidin-3-ol

Frequently asked questions

What are the approved indications of AQW-051?

Approved indications include: Anxiety, 表现焦虑, Alzheimer's disease, Mild cognitive impairment, Schizophrenia, 运动障碍.

When does the AQW-051 patent expire?

No public expiry year is available for AQW-051 yet; this page updates once verified.

How many synthesis routes are recorded for AQW-051?

1 synthesis routes are recorded; the shortest is 3 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy AQW-051 intermediates?

All intermediates in AQW-051 routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for AQW-051 intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-30