Ganaxolone
Tier C — Watch / tradeGanaxolone
Targets：GABAAR
Brand：ZTALMY
Indications (approved)：CDKL5缺乏症, Seizure, 癫痫综合征, 婴儿痉挛
Regional status
Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| GANA-001 | 1452-23-9 | (5S,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-17-(2-methyl-1,3-dioxolan-2-yl)hexadecahydro-3H-cyclopenta[a]phenanthren-3-one |
| GANA-002 | 148256-46-6 | (3R,5S,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-17-(2-methyl-1,3-dioxolan-2-yl)hexadecahydrospiro[cyclopenta[a]phenanthrene-3,2'-oxirane] |
| GANA-003 | 55571-86-3 | (3R,5S,8R,9S,10S,13S,14S,17S)-3,10,13-trimethyl-17-(2-methyl-1,3-dioxolan-2-yl)hexadecahydro-1H-cyclopenta[a]phenanthren-3-ol |
| Code | CAS No. | Intermediate |
|---|---|---|
| GANA-004 | 566-65-4 | (5S,8R,9S,10S,13S,14S,17S)-17-acetyl-10,13-dimethylhexadecahydro-3H-cyclopenta[a]phenanthren-3-one |
| GANA-005 | 148256-45-5 | 1-((3R,5S,8R,9S,10S,13S,14S,17S)-10,13-dimethylhexadecahydrospiro[cyclopenta[a]phenanthrene-3,2'-oxiran]-17-yl)ethan-1-one |
| Code | CAS No. | Intermediate |
|---|---|---|
| GANA-004 | 566-65-4 | (5S,8R,9S,10S,13S,14S,17S)-17-acetyl-10,13-dimethylhexadecahydro-3H-cyclopenta[a]phenanthren-3-one |
Frequently asked questions
What are the approved indications of Ganaxolone?
Approved indications include: CDKL5缺乏症, Seizure, 癫痫综合征, 婴儿痉挛.
When does the Ganaxolone patent expire?
No public expiry year is available for Ganaxolone yet; this page updates once verified.
How many synthesis routes are recorded for Ganaxolone?
3 synthesis routes are recorded; the shortest is 1 steps with 0.983 kg total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Ganaxolone intermediates?
All intermediates in Ganaxolone routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Ganaxolone intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29