Palovarotene
Tier C — Watch / tradePalovarotene
Targets：RAR-γ
Brand：Sohonos
Indications (approved)：进行性肌肉骨化症
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| PALOV-001 | 110-03-2 | 2,5-dimethylhexane-2,5-diol |
| PALOV-002 | 6223-78-5 | 2,5-dichloro-2,5-dimethylhexane |
| PALOV-003 | 95-46-5 | 1-bromo-2-methylbenzene |
| PALOV-004 | 119999-22-3 | 6-bromo-1,1,4,4,7-pentamethyl-1,2,3,4-tetrahydronaphthalene |
| PALOV-005 | 58243-83-7 | 3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalene-2-carbonitrile |
| PALOV-006 | 17610-20-7 | 3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalene-2-carbaldehyde |
| PALOV-007 | 78022-19-2 | methyl 4-((dimethoxyphosphoryl)methyl)benzoate |
| PALOV-008 | 410528-53-9 | (E)-methyl 4-(2-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoate |
| PALOV-009 | 410528-54-0 | (E)-methyl 4-(2-(3-(bromomethyl)-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoate |
| PALOV-010 | 288-13-1Available | 1H-pyrazole |
| PALOV-011 | 410528-55-1 | (E)-methyl 4-(2-(3-((1H-pyrazol-1-yl)methyl)-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl)benzoate |
Frequently asked questions
What are the approved indications of Palovarotene?
Approved indications include: 进行性肌肉骨化症.
When does the Palovarotene patent expire?
No public expiry year is available for Palovarotene yet; this page updates once verified.
How many synthesis routes are recorded for Palovarotene?
1 synthesis routes are recorded; the shortest is 8 steps with 25.9 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Palovarotene intermediates?
1 intermediate CAS of Palovarotene are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Palovarotene intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29