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Fentanyl

Tier C — Watch / trade

Fentanyl

Johnson & Johnson Innovative Medicine
Originator
1990
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:MOR1

Brand:Duragesic, OneDuro, Fenrock, Subsys

Indications (approved):Pain

Regional status

US
Withdrawn
EU
No progress
2013-03-01
China
Approved
2004-01-21
Japan
No progress
2007-12-01

Synthetic routes & intermediates1 routes

Originator routes × 0Optimised (non-patent) × 1Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OptimisedRoute 1Steps 3 · Total yield 1.53 g (Fentanyl)
FENT-001320589-77-3FENT-002103-63-9FENT-00339742-60-4FENT-00462-53-3FENT-00521409-26-7FENT-00679-03-8API · Fentanyl
CodeCAS No.Intermediate
FENT-001320589-77-3piperidin-4-one hydrochloride hydrate
FENT-002103-63-9(2-bromoethyl)benzene
FENT-00339742-60-41-phenethylpiperidin-4-one
FENT-00462-53-3Availableaniline
FENT-00521409-26-71-phenethyl-N-phenylpiperidin-4-amine
FENT-00679-03-8(8R,9S,10R,13S,14S,17R)-17-(2-hydroxyacetyl)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl pentanoate

Frequently asked questions

What are the approved indications of Fentanyl?

Approved indications include: Pain.

When does the Fentanyl patent expire?

No public expiry year is available for Fentanyl yet; this page updates once verified.

How many synthesis routes are recorded for Fentanyl?

1 synthesis routes are recorded; the shortest is 3 steps with 1.53 g (Fentanyl) total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Fentanyl intermediates?

1 intermediate CAS of Fentanyl are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Fentanyl intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29