Azacitidine
Tier C — Watch / tradeAzacitidine
Targets：DNMT1
Brand：Vidaza, Onureg
Indications (approved)：幼年型粒单核细胞白血病, Acute myeloid leukaemia, Myelodysplastic syndrome, Chronic myeloid leukaemia, Chronic myelomonocytic leukaemia
Regional status
Factories producing this API4
Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.
4 producing factories on file — sign in to view the named list (factory details are not shown to guests).
Sign in to view factories →Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| AZAC-001 | 59285-13-1 | (2R,3R,4R,5R)-2-(acetoxymethyl)-5-isocyanatotetrahydrofuran-3,4-diyl diacetate |
| AZAC-002 | 2986-19-8 | methyl carbamimidothioate |
| AZAC-003 | 4654-72-2 | (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(3-((E)-amino(methylthio)methylene)ureido)tetrahydrofuran-3,4-diyl diacetate |
| AZAC-004 | 4654-73-3 | (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(4-(methylthio)-2-oxo-1,3,5-triazin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate |
| Code | CAS No. | Intermediate |
|---|---|---|
| AZAC-005 | 931-86-2 | 4-amino-1,3,5-triazin-2(1H)-one |
| AZAC-006 | 52523-35-0 | N-(trimethylsilyl)-4-((trimethylsilyl)oxy)-1,3,5-triazin-2-amine |
| AZAC-007 | 13035-61-5Available | (2S,3R,4R,5R)-5-(acetoxymethyl)tetrahydrofuran-2,3,4-triyl triacetate |
| AZAC-009 | 461-58-5 | - |
| AZAC-010 | 64-18-6 | N-Methylformamide-001 |
| AZAC-011 | 141-83-3 | 1-(diaminomethylene)urea |
| AZAC-012 | 10302-78-0 | (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(4-amino-2-oxo-1,3,5-triazin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate |
| Code | CAS No. | Intermediate |
|---|---|---|
| AZAC-005 | 931-86-2 | 4-amino-1,3,5-triazin-2(1H)-one |
| AZAC-006 | 52523-35-0 | N-(trimethylsilyl)-4-((trimethylsilyl)oxy)-1,3,5-triazin-2-amine |
| AZAC-007 | 13035-61-5Available | (2S,3R,4R,5R)-5-(acetoxymethyl)tetrahydrofuran-2,3,4-triyl triacetate |
| AZAC-008 | 766536-90-7 | (2R,3R,4R,5R)-2-(acetoxymethyl)-5-(2-oxo-4-((trimethylsilyl)amino)-1,3,5-triazin-1(2H)-yl)tetrahydrofuran-3,4-diyl diacetate |
Frequently asked questions
What are the approved indications of Azacitidine?
Approved indications include: 幼年型粒单核细胞白血病, Acute myeloid leukaemia, Myelodysplastic syndrome, Chronic myeloid leukaemia, Chronic myelomonocytic leukaemia.
When does the Azacitidine patent expire?
No public expiry year is available for Azacitidine yet; this page updates once verified.
How many synthesis routes are recorded for Azacitidine?
3 synthesis routes are recorded; the shortest is 3 steps with 1.65g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Azacitidine intermediates?
1 intermediate CAS of Azacitidine are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Azacitidine intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29