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Dalfampridine

Tier C — Watch / trade

Dalfampridine

Acorda Therapeutics Inc
Originator
2010
First approval
-
Expiry (public)
$0.63B ▲
Peak sales
Small molecule
Type

Targets:Potassium channel, VGKCs

Brand:Fampyra, Neurelan, Amaya, Ampyra

Indications (approved):Multiple sclerosis

Regional status

US
Approved
2010-01-22
EU
Approved
2011-07-20
China
Approved
2021-05-11
Japan
No progress
2013-08-01

Factories producing this API3

Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.

3 producing factories on file — sign in to view the named list (factory details are not shown to guests).

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Synthetic routes & intermediates4 routes

Originator routes × 1Optimised (non-patent) × 3Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 2 · Total yield /
Synthetic routes & intermediates Route 1
CodeCAS No.Intermediate
DALF-001110-86-1pyridine
DALF-0025421-92-1[1,4'-bipyridine]-1,1'-diium chloride
OptimisedRoute 2Steps 1 · Total yield /
Synthetic routes & intermediates Route 2
CodeCAS No.Intermediate
DALF-00355-22-1isonicotinic acid
OptimisedRoute 3Steps 2 · Total yield 70 g
Synthetic routes & intermediates Route 3
CodeCAS No.Intermediate
DALF-004-pyridine 1-oxide hydrochloride
DALF-0051124-33-04-nitropyridine 1-oxide
OptimisedRoute 4Steps 1 · Total yield 8.2 g
Synthetic routes & intermediates Route 4
CodeCAS No.Intermediate
DALF-006100-48-1isonicotinonitrile

Frequently asked questions

What are the approved indications of Dalfampridine?

Approved indications include: Multiple sclerosis.

When does the Dalfampridine patent expire?

No public expiry year is available for Dalfampridine yet; this page updates once verified.

How many synthesis routes are recorded for Dalfampridine?

4 synthesis routes are recorded; the shortest is 1 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Dalfampridine intermediates?

All intermediates in Dalfampridine routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Dalfampridine intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29