MRX-2843
Tier C — Watch / tradeMRX-2843
Targets：FLT3, MerTK
Indications (approved)：Acute myeloid leukaemia, Leukaemia, Acute lymphoblastic leukaemia, Non-small cell lung cancer, Lung cancer, Solid tumour, 病理过程, 肿瘤形成过程
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| MRX-2843 | 1429882-07-4 | - |
| MRX-2843-001 | 1060816-58-1 | 5-bromo-2-chloro-7H-pyrrolo[2,3-d]pyrimidine |
| MRX-2843-002 | 103202-62-6 | (1s,4s)-4-((tert-butyldimethylsilyl)oxy)cyclohexanol |
| MRX-2843-003 | 176325-83-0 | 5-bromo-7-((1r,4r)-4-((tert-butyldimethylsilyl)oxy)cyclohexyl)-2-chloro-7H-pyrrolo[2,3-d]pyrimidine |
| MRX-2843-004 | 62893-54-3 | 2-cyclopropylethanamine |
| MRX-2843-005 | 1621619-16-6 | 5-bromo-7-((1r,4r)-4-((tert-butyldimethylsilyl)oxy)cyclohexyl)-N-(2-cyclopropylethyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine |
| MRX-2843-006 | 763120-62-3 | (4-((4-methylpiperazin-1-yl)methyl)phenyl)boronic acid |
| MRX-2843-007 | - | 7-((1r,4r)-4-((tert-butyldimethylsilyl)oxy)cyclohexyl)-N-(2-cyclopropylethyl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine |
Frequently asked questions
What are the approved indications of MRX-2843?
Approved indications include: Acute myeloid leukaemia, Leukaemia, Acute lymphoblastic leukaemia, Non-small cell lung cancer, Lung cancer, Solid tumour, 病理过程, 肿瘤形成过程.
When does the MRX-2843 patent expire?
No public expiry year is available for MRX-2843 yet; this page updates once verified.
How many synthesis routes are recorded for MRX-2843?
1 synthesis routes are recorded; the shortest is 4 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy MRX-2843 intermediates?
All intermediates in MRX-2843 routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for MRX-2843 intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-06