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Veliparib Hydrochloride

Tier C — Watch / trade

Veliparib Hydrochloride

AbbVie
Originator
-
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:PARP-2, PARP1

Indications (approved):Glioblastoma, 神经胶质肉瘤, Metastatic breast cancer, Glioma, 星形细胞瘤, Myelofibrosis, 骨髓增生异常-骨髓增生性疾病, Acute myeloid leukaemia

Regional status

US
Phase III
2014-04-02
EU
Phase III
2014-04-02
China
IND filed
2016-11-30
Japan
Discontinued
2014-09-30

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 5 · Total yield 254 mg
VELI-001108645-62-1VELI-002141870-95-3VELI-00363427-91-8VELI-004711007-44-2VELI-005912444-71-4VELI-006912444-73-6API · Veliparib Hydrochloride
CodeCAS No.Intermediate
VELI-001108645-62-11-benzyl 2-methyl pyrrolidine-1,2-dicarboxylate
VELI-002141870-95-31-benzyl 2-methyl 2-methylpyrrolidine-1,2-dicarboxylate
VELI-00363427-91-81-((benzyloxy)carbonyl)-2-methylpyrrolidine-2-carboxylic acid
VELI-004711007-44-22,3-diaminobenzamide
VELI-005912444-71-4benzyl 2-((2-amino-3-carbamoylphenyl)carbamoyl)-2-methylpyrrolidine-1-carboxylate
VELI-006912444-73-6(R)-benzyl 2-(4-carbamoyl-1H-benzo[d]imidazol-2-yl)-2-methylpyrrolidine-1-carboxylate

Frequently asked questions

What are the approved indications of Veliparib Hydrochloride?

Approved indications include: Glioblastoma, 神经胶质肉瘤, Metastatic breast cancer, Glioma, 星形细胞瘤, Myelofibrosis, 骨髓增生异常-骨髓增生性疾病, Acute myeloid leukaemia.

When does the Veliparib Hydrochloride patent expire?

No public expiry year is available for Veliparib Hydrochloride yet; this page updates once verified.

How many synthesis routes are recorded for Veliparib Hydrochloride?

1 synthesis routes are recorded; the shortest is 5 steps with 254 mg total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Veliparib Hydrochloride intermediates?

All intermediates in Veliparib Hydrochloride routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Veliparib Hydrochloride intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-10-12