Alosetron Hydrochloride
Tier C — Watch / tradeAlosetron Hydrochloride
Targets：5-HT3
Brand：Lotronex
Indications (approved)：Irritable bowel syndrome
Regional status
Synthetic routes & intermediates3 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| ALOS-001 | 50776-26-6 | 4-methyl-3,4-dihydrocyclopenta[b]indol-1(2H)-one |
| ALOS-002 | 122852-74-8 | (E)-4-methyl-3,4-dihydrocyclopenta[b]indol-1(2H)-one oxime |
| ALOS-003 | 122852-75-9 | 5-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one |
| ALOS-004 | 131099-78-0 | 5-(chloromethyl)-4-methyl-1-trityl-1H-imidazole |
| Code | CAS No. | Intermediate |
|---|---|---|
| ALOS-003 | 122852-75-9 | 5-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one |
| ALOS-005 | 29636-87-1 | (4-methyl-1H-imidazol-5-yl)methanol |
| ALOS-006 | 307504-13-8 | tert-butyl 5-(hydroxymethyl)-4-methyl-1H-imidazole-1-carboxylate |
| Code | CAS No. | Intermediate |
|---|---|---|
| ALOS-007 | 7088-88-2 | 2-(1-methyl-1H-indol-2-yl)ethan-1-amine |
| ALOS-008 | 122853-01-4 | 2,2,2-trifluoro-N-(2-(1-methyl-1H-indol-2-yl)ethyl)acetamide |
| ALOS-009 | - | 5-(chloromethyl)-N,N,4-trimethyl-1H-imidazole-1-sulfonamide |
| ALOS-010 | 122853-02-5 | N-((1-(N,N-dimethylsulfamoyl)-5-methyl-1H-imidazol-4-yl)methyl)-2,2,2-trifluoro-N-(2-(1-methyl-1H-indol-2-yl)ethyl)acetamide |
Frequently asked questions
What are the approved indications of Alosetron Hydrochloride?
Approved indications include: Irritable bowel syndrome.
When does the Alosetron Hydrochloride patent expire?
No public expiry year is available for Alosetron Hydrochloride yet; this page updates once verified.
How many synthesis routes are recorded for Alosetron Hydrochloride?
3 synthesis routes are recorded; the shortest is 2 steps with 7.8 g total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Alosetron Hydrochloride intermediates?
All intermediates in Alosetron Hydrochloride routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Alosetron Hydrochloride intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29