Pafolacianine Sodium

Tier C — Watch / trade

On Target Laboratories Inc

Originator

2021

First approval

Expiry (public)

No sales data

Peak sales

In vivo diagnostic

Type

Targets：FOLR1

Brand：Cytalux

Indications (approved)：Lung cancer, Ovarian cancer

Regional status

Approved

2021-11-29

Phase II

2017-05-04

China

Japan

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 4 · Total yield 31 g

OTL-38-001—OTL-38-002—OTL-38-003—OTL-38-004—OTL-38-005—OTL-38-006—API · Pafolacianine Sodium

Code	CAS No.	Intermediate
OTL-38-001	-	-
OTL-38-002	-	-
OTL-38-003	-	4-(((2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl)((trifluoromethoxy)carbonyl)amino)benzoic acid
OTL-38-004	-	-
OTL-38-005	-	(4-(((2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl)((trifluoromethoxy)carbonyl)amino)benzoyl)-L-tyrosine
OTL-38-006	-	2-((E)-2-((E)-2-chloro-3-(2-((E)-3,3-dimethyl-5-sulfonato-1-(4-sulfonatobutyl)indolin-2-ylidene)ethylidene)cyclohex-1-en-1-yl)vinyl)-3,3-dimethyl-1-(4-sulfonatobutyl)-3H-indol-1-ium-5-sulfonate sodium （1:4）

Frequently asked questions

What are the approved indications of Pafolacianine Sodium?

Approved indications include: Lung cancer, Ovarian cancer.

When does the Pafolacianine Sodium patent expire?

No public expiry year is available for Pafolacianine Sodium yet; this page updates once verified.

How many synthesis routes are recorded for Pafolacianine Sodium?

1 synthesis routes are recorded; the shortest is 4 steps with 31 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Pafolacianine Sodium intermediates?

All intermediates in Pafolacianine Sodium routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Pafolacianine Sodium intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29