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Gadoxetate Disodium

Tier C — Watch / trade

Gadoxetate Disodium

Bayer
Originator
2004
First approval
-
Expiry (public)
No sales data
Peak sales
In vivo diagnostic
Type

Targets:Not applicable

Brand:Primovist, Eovist

Indications (approved):Contrast imaging, Diagnostic agent

Regional status

US
Approved
2008-07-03
EU
Approved
2004-03-26
China
Approved
2010-09-25
Japan
Approved
2007-10-19

Factories producing this API2

Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.

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Synthetic routes & intermediates2 routes

Originator routes × 1Optimised (non-patent) × 1Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 1 · Total yield 1.7 g (Gadoxetate)
GADO-001158043-55-1Gadoxetate135306-78-4API · Gadoxetate Disodium
CodeCAS No.Intermediate
GADO-001158043-55-1(S)-N1-(2-aminoethyl)-3-(4-ethoxyphenyl)propane-1,2-diamine
Gadoxetate135306-78-4(S)-2,2'-((2-((2-(bis(carboxymethyl)amino)-3-(4-ethoxyphenyl)propyl)(carboxymethyl)amino)ethyl)azanediyl)diacetic acid
OptimisedRoute 2Steps 9 · Total yield 108 g (Gadoxetate sodium)
GADO-00260-18-4GADO-0033978-80-1GADO-00476757-91-0GADO-0051252686-29-5GADO-0061618674-24-0GADO-0071618674-23-9GADO-0082226923-94-8GADO-009213312-49-3Gadoxetate sodium135326-11-3API · Gadoxetate Disodium
CodeCAS No.Intermediate
GADO-00260-18-4L-tyrosine
GADO-0033978-80-1(tert-butoxycarbonyl)-L-tyrosine
GADO-00476757-91-0(S)-2-((tert-butoxycarbonyl)amino)-3-(4-ethoxyphenyl)propanoic acid
GADO-0051252686-29-5tert-butyl (S)-(1-(4-ethoxyphenyl)-3-hydroxypropan-2-yl)carbamate
GADO-0061618674-24-0(S)-2-((tert-butoxycarbonyl)amino)-3-(4-ethoxyphenyl)propyl methanesulfonate
GADO-0071618674-23-9tert-butyl (S)-(1-((2-aminoethyl)amino)-3-(4-ethoxyphenyl)propan-2-yl)carbamate
GADO-0082226923-94-8(S)-N1-(2-aminoethyl)-3-(4-ethoxyphenyl)propane-1,2-diamine hydrochloride
GADO-009213312-49-3di-tert-butyl 2,2'-((2-((2-(bis(2-(tert-butoxy)-2-oxoethyl)amino)-3-(4-ethoxyphenyl)propyl)(2-(tert-butoxy)-2-oxoethyl)amino)ethyl)azanediyl)(S)-diacetate
Gadoxetate sodium135326-11-3-

Frequently asked questions

What are the approved indications of Gadoxetate Disodium?

Approved indications include: Contrast imaging, Diagnostic agent.

When does the Gadoxetate Disodium patent expire?

No public expiry year is available for Gadoxetate Disodium yet; this page updates once verified.

How many synthesis routes are recorded for Gadoxetate Disodium?

2 synthesis routes are recorded; the shortest is 1 steps with 1.7 g (Gadoxetate) total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Gadoxetate Disodium intermediates?

All intermediates in Gadoxetate Disodium routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Gadoxetate Disodium intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29