Timolol Maleate
Tier C — Watch / tradeTimolol Maleate
Targets：β-adrenoceptors
Brand：Timoptol-la, Betim, Timosan, Rysmon TG, Istalol, Timolast, Timoptol-lp, Nyolol, Timoptic-XE, TIMOPTIC-PF, Blocadren, Timoptic, Timacor, Timoptol, Timoptol XE, Nyogel
Indications (approved)：Ocular hypertension, Glaucoma, Open-angle glaucoma
Regional status
Synthetic routes & intermediates2 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| Timolol Maleate-001 | 30165-97-0 | 4-(4-Morpholinyl)-1,2,5-thiadiazol-3-ol |
| Timolol Maleate-002 | 106-89-8 | (+/-)-2-(Chloromethyl)oxirane |
| Timolol Maleate-003 | 75-64-9Available | 2-Methylpropan-2-amine |
| Timolol Maleate-004 | 29023-48-1 | 1-(tert-Butylamino)-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol |
| Timolol Maleate-005 | 26839-75-8 | (S)-1-(tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol |
| Timolol Maleate-006 | 5728-20-1 | 3,4-Dichloro-1,2,5-thiadiazole |
| Timolol Maleate-007 | 110-91-8Available | Diethylene oximide |
| Timolol Maleate-008 | 30165-96-9 | 4-(4-chloro-1,2,5-thiadiazol-3-yl)morpholine |
| Timolol Maleate-009 | 30315-47-0 | [(5S)-3-tert-Butyl-1,3-oxazolidin-5-yl]methanol |
| Code | CAS No. | Intermediate |
|---|---|---|
| Timolol Maleate-002 | 106-89-8 | 2-(Chloromethyl)oxirane |
| Timolol Maleate-010 | 51594-55-9 | (R)-(-)-2-(Chloromethyl)oxirane |
| Timolol Maleate-011 | 60827-45-4 | 3-Chloropropane-1,2(S)-diol |
| Timolol Maleate-001 | 30165-97-0 | 4-(4-Morpholinyl)-1,2,5-thiadiazol-3-ol |
| Timolol Maleate-012 | 935528-00-0 | (2R)-1-Chloro-3-[[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propan-2-ol |
| Timolol Maleate-013 | 69500-53-4 | 4-[4-[(2S)-Oxiran-2-ylmethoxy]-1,2,5-thiadiazol-3-yl]morpholine |
| Timolol Maleate-014 | - | Sodium 4-(morpholin-4-yl)-1,2,5-thiadiazol-3-olate |
| Timolol Maleate-015 | 295776-81-7 | (2S)-3-[[4-(Morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy]propane-1,2-diol |
| Timolol Maleate-003 | 75-64-9Available | 2-Methylpropan-2-amine |
| Timolol Maleate-005 | 26839-75-8 | (S)-1-(tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol |
Frequently asked questions
What are the approved indications of Timolol Maleate?
Approved indications include: Ocular hypertension, Glaucoma, Open-angle glaucoma.
When does the Timolol Maleate patent expire?
No public expiry year is available for Timolol Maleate yet; this page updates once verified.
How many synthesis routes are recorded for Timolol Maleate?
2 synthesis routes are recorded; the shortest is 5 steps with 108.7g(Timolol Maleate (API)) total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Timolol Maleate intermediates?
2 intermediate CAS of Timolol Maleate are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Timolol Maleate intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29