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Vericiguat

Tier C — Watch / trade

Vericiguat

Bayer
Originator
2021
First approval
-
Expiry (public)
No sales data
Peak sales
Small molecule
Type

Targets:sGC

Brand:Verquvo

Indications (approved):Heart failure

Regional status

US
Approved
2021-01-19
EU
Approved
2021-07-16
China
Approved
2022-05-18
Japan
Approved
2021-06-23

Factories producing this API1

Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.

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Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 9 · Total yield 24.24 g
VERI-00182671-02-1VERI-002113237-20-0VERI-00375302-64-6VERI-004791644-48-9VERI-0051034667-22-5VERI-006110-46-3VERI-0071350653-23-4VERI-008446-48-0VERI-0091350653-24-5VERI-010408352-74-9VERI-0111350653-25-6VERI-0121350653-30-3API · Vericiguat
CodeCAS No.Intermediate
VERI-00182671-02-1Available2,6-dichloro-5-fluoronicotinonitrile
VERI-002113237-20-0Available2,6-dichloro-5-fluoronicotinamide
VERI-00375302-64-6Available2-chloro-5-fluoronicotinamide
VERI-004791644-48-9Available2-chloro-5-fluoronicotinonitrile
VERI-0051034667-22-5Available5-fluoro-1H-pyrazolo[3,4-b]pyridin-3-amine
VERI-006110-46-3Availableisopentyl nitrite
VERI-0071350653-23-4Available5-fluoro-3-iodo-1H-pyrazolo[3,4-b]pyridine
VERI-008446-48-0Available1-(bromomethyl)-2-fluorobenzene
VERI-0091350653-24-5Available5-fluoro-1-(2-fluorobenzyl)-3-iodo-1H-pyrazolo[3,4-b]pyridine
VERI-010408352-74-9Available2-chloro-5-nitropyrimidine-4,6-diamine
VERI-0111350653-25-6Available2-(5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-5-nitropyrimidine-4,6-diamine
VERI-0121350653-30-3Available2-(5-fluoro-1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)pyrimidine-4,5,6-triamine

Frequently asked questions

What are the approved indications of Vericiguat?

Approved indications include: Heart failure.

When does the Vericiguat patent expire?

No public expiry year is available for Vericiguat yet; this page updates once verified.

How many synthesis routes are recorded for Vericiguat?

1 synthesis routes are recorded; the shortest is 9 steps with 24.24 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Vericiguat intermediates?

12 intermediate CAS of Vericiguat are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Vericiguat intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29