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Naftopidil

Tier C — Watch / trade

Naftopidil

F. Hoffmann-La Roche
Originator
1998
First approval
-
Expiry (public)
$0.18B ▲
Peak sales
Small molecule
Type

Targets:ADRA1

Brand:Avishot, Flivas, Eapidil

Indications (approved):排尿困难, Benign prostatic hyperplasia

Regional status

US
-
EU
-
China
Approved
2001-01-01
Japan
Approved
1998-12-25

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 2 · Total yield /
NAFT-00190-15-3NAFT-002106-89-8NAFT-0032461-42-9NAFT-0045464-78-8API · Naftopidil
CodeCAS No.Intermediate
NAFT-00190-15-3naphthalen-1-ol
NAFT-002106-89-82-(chloromethyl)oxirane
NAFT-0032461-42-92-((naphthalen-1-yloxy)methyl)oxirane
NAFT-0045464-78-81-(2-methoxyphenyl)piperazine hydrochloride

Frequently asked questions

What are the approved indications of Naftopidil?

Approved indications include: 排尿困难, Benign prostatic hyperplasia.

When does the Naftopidil patent expire?

No public expiry year is available for Naftopidil yet; this page updates once verified.

How many synthesis routes are recorded for Naftopidil?

1 synthesis routes are recorded; the shortest is 2 steps with / total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Naftopidil intermediates?

All intermediates in Naftopidil routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.

How do I get a quote for Naftopidil intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29