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Chidamide

Tier C — Watch / trade

Chidamide

Shenzhen Chipscreen Biosciences Co., Ltd.
Originator
2014
First approval
-
Expiry (public)
$0.07B ▲
Peak sales
Small molecule
Type

Targets:Ras, C-akt, MAPKs, HDAC3, HDAC2, HDAC10, HDAC1

Brand:Epidaza, Hiyasta

Indications (approved):Diffuse large B-cell lymphoma, T-cell leukaemia, Breast cancer, Peripheral T-cell lymphoma

Regional status

US
-
EU
-
China
Approved
2014-12-23
Japan
Approved
2021-06-24

Synthetic routes & intermediates1 routes

Originator routes × 1Optimised (non-patent) × 0Process routes × 0

Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.

OriginatorRoute 1Steps 3 · Total yield 201.2 g
Synthetic routes & intermediates Route 1
CodeCAS No.Intermediate
CHID-001500-22-1nicotinaldehyde
CHID-002141-82-2Availablemalonic acid
CHID-00319337-97-4(E)-3-(pyridin-3-yl)acrylic acid
CHID-00456-91-74-(aminomethyl)benzoic acid
CHID-005219964-34-8(E)-4-((3-(pyridin-3-yl)acrylamido)methyl)benzoic acid
CHID-006367-31-74-fluorobenzene-1,2-diamine

Frequently asked questions

What are the approved indications of Chidamide?

Approved indications include: Diffuse large B-cell lymphoma, T-cell leukaemia, Breast cancer, Peripheral T-cell lymphoma.

When does the Chidamide patent expire?

No public expiry year is available for Chidamide yet; this page updates once verified.

How many synthesis routes are recorded for Chidamide?

1 synthesis routes are recorded; the shortest is 3 steps with 201.2 g total yield. Intermediates in each route carry codes and CAS numbers.

Where can I buy Chidamide intermediates?

1 intermediate CAS of Chidamide are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.

How do I get a quote for Chidamide intermediates?

Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.

Source: cross-verified data (structured fields only) · 2026-09-29