Nadolol
Tier C — Watch / tradeNadolol
Targets：β-adrenoceptors
Brand：Corgard, Corgaretic, Nadic
Indications (approved)：Diabetic macular oedema, Diabetic retinopathy, 感染性角结膜炎, Dry eye syndrome, Hypertension, Hyperthyroidism, Migraine, 心动过缓
Regional status
Synthetic routes & intermediates2 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| Nadolol-001 | 27673-48-9 | 5,8-Dihydro-1-naphthol |
| Nadolol-002 | 830-81-9 | alpha-Naphthyl acetate |
| Nadolol-003 | 2165726-81-6 | cis-6,7-Dihydroxy-5,6,7,8-tetrahydronaphthalen-1-yl acetate |
| Nadolol-004 | 147331-60-0 | (6R,7S)-5,6,7,8-Tetrahydronaphthalene-1,6,7-triol |
| Nadolol-005 | - | Sodium cis-6,7-dihydroxy-5,6,7,8-tetrahydronaphthalen-1-olate |
| Nadolol-006 | 106-89-8 | (+/-)-2-(Chloromethyl)oxirane |
| Nadolol-007 | 1430052-97-3 | (2R,3S)-5-(Oxiran-2-ylmethoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol |
| Nadolol-008 | 75-64-9Available | 2-Methylpropan-2-amine |
| Code | CAS No. | Intermediate |
|---|---|---|
| Nadolol-009 | 27673-47-8 | 2-[(5,8-dihydronaphthalen-1-yloxy)methyl]oxirane |
| Nadolol-010 | 67247-34-1 | tert-butyl[3-(5,8-dihydronaphthalen-1-yloxy)-2-hydroxypropyl]amine |
| Nadolol-008 | 75-64-9Available | tert-Butylamine |
Frequently asked questions
What are the approved indications of Nadolol?
Approved indications include: Diabetic macular oedema, Diabetic retinopathy, 感染性角结膜炎, Dry eye syndrome, Hypertension, Hyperthyroidism, Migraine, 心动过缓.
When does the Nadolol patent expire?
No public expiry year is available for Nadolol yet; this page updates once verified.
How many synthesis routes are recorded for Nadolol?
2 synthesis routes are recorded; the shortest is 2 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Nadolol intermediates?
1 intermediate CAS of Nadolol are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Nadolol intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-22