Oltipraz
Tier C — Watch / tradeOltipraz
Targets：Nrf2
Indications (approved)：Non-alcoholic steatohepatitis, Lung cancer, Liver cirrhosis
Regional status
Synthetic routes & intermediates1 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| OLTI-001 | 98-97-5 | pyrazine-2-carboxylic acid |
| OLTI-002 | 6164-79-0 | methyl pyrazine-2-carboxylate |
| OLTI-003 | 554-12-1 | methyl propionate |
| OLTI-004 | 324737-10-2 | methyl 2-methyl-3-oxo-3-(pyrazin-2-yl)propanoate |
| Oltipraz | 64224-21-1 | 4-methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione |
Frequently asked questions
What are the approved indications of Oltipraz?
Approved indications include: Non-alcoholic steatohepatitis, Lung cancer, Liver cirrhosis.
When does the Oltipraz patent expire?
No public expiry year is available for Oltipraz yet; this page updates once verified.
How many synthesis routes are recorded for Oltipraz?
1 synthesis routes are recorded; the shortest is 3 steps with 6.37 g (Oltipraz) total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Oltipraz intermediates?
All intermediates in Oltipraz routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Oltipraz intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-10-12