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Tamsulosin Hydrochloride
Tier C — Watch / tradeTamsulosin Hydrochloride
Astellas Pharma Inc.
Originator
1993
First approval
-
Expiry (public)
$0.78B ▲
Peak sales
Small molecule
Type
Targets：ADRA1A
Brand：Alna, Flomax, Omnic, Contiflo XL, Omix, Harnal, Secotex, Flomaxtra, Josir, Harnal D, Pradif, Harnalidge OCAS, Hanmi Tams, Urolosin, AlnaOCAS, Urimax, Omic, Flomax MR
Indications (approved)：Benign prostatic hyperplasia
Regional status
US
Phase III
2008-01-01
EU
Phase II
2006-04-01
China
Approved
1999-04-03
Japan
Approved
1993-01-01
Factories producing this API1
Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.
1 producing factories on file — sign in to view the named list (factory details are not shown to guests).
Sign in to view factories →Synthetic routes & intermediates21 routes
Originator routes × 0Optimised (non-patent) × 19Process routes × 2
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
OptimisedRoute 1Steps 9 · Total yield 50.8g(Tamsulosin (Free))
Tamsulosin Hydrochloride-001122-84-9Tamsulosin Hydrochloride-0023886-69-9Tamsulosin Hydrochloride-003—Tamsulosin Hydrochloride-004121565-95-5Tamsulosin Hydrochloride-005112101-75-4Tamsulosin Hydrochloride-006116091-64-6Tamsulosin Hydrochloride-007103181-55-1Tamsulosin Hydrochloride-008106133-20-4Tamsulosin Hydrochloride-0093259-03-8Tamsulosin Hydrochloride-01094-71-3Tamsulosin Hydrochloride-01196-49-1Tamsulosin Hydrochloride-0123250-73-5API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-001 | 122-84-9 | 1-(4-Methoxyphenyl)-2-propanone |
| Tamsulosin Hydrochloride-002 | 3886-69-9Available | (R)-(-)-1-Phenylethylamine |
| Tamsulosin Hydrochloride-003 | - | (2R)-1-(4-Methoxyphenyl)-N-[(1R)-1-phenylethyl]propan-2-amine hydrochloride |
| Tamsulosin Hydrochloride-004 | 121565-95-5 | 2-Methoxy-5-[(2R)-2-[[(1R)-1-phenylethyl]amino]propyl]benzenesulfonamide |
| Tamsulosin Hydrochloride-005 | 112101-75-4 | 5-[(2R)-2-Aminopropyl]-2-methoxybenzenesulfonamide hydrochloride |
| Tamsulosin Hydrochloride-006 | 116091-64-6 | 2-Methoxy-5-[(2R)-2-[[(1R)-1-phenylethyl]amino]propyl]benzenesulfonamide hydrochloride |
| Tamsulosin Hydrochloride-007 | 103181-55-1 | (2-Ethoxyphenoxy)acetaldehyde |
| Tamsulosin Hydrochloride-008 | 106133-20-4 | (-)-5-[2(R)-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide |
| Tamsulosin Hydrochloride-009 | 3259-03-8 | 1-(2-Bromoethoxy)-2-ethoxybenzene |
| Tamsulosin Hydrochloride-010 | 94-71-3 | 1-Hydroxy-2-ethoxybenzene |
| Tamsulosin Hydrochloride-011 | 96-49-1 | 1,3-Dioxolan-2-one |
| Tamsulosin Hydrochloride-012 | 3250-73-5 | 2-(2-Ethoxyphenoxy)ethanol |
OptimisedRoute 2Steps 5 · Total yield 1.2g(Tamsulosin (Free))
Tamsulosin Hydrochloride-01386225-70-9Tamsulosin Hydrochloride-014434312-10-4Tamsulosin Hydrochloride-015—Tamsulosin Hydrochloride-016—Tamsulosin Hydrochloride-017754930-54-6Tamsulosin Hydrochloride-018760126-31-6API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-013 | 86225-70-9 | 5-(2-bromopropanoyl)-2-methoxybenzenesulfonamide |
| Tamsulosin Hydrochloride-014 | 434312-10-4 | benzyl[2-(2-ethoxyphenoxy)ethyl]amine |
| Tamsulosin Hydrochloride-015 | - | 5-(2-{benzyl[2-(2-ethoxyphenoxy)ethyl]amino}propanoyl)-2-methoxybenzenesulfonamide |
| Tamsulosin Hydrochloride-016 | - | 5-(2-{benzyl[2-(2-ethoxyphenoxy)ethyl]amino}-1-hydroxypropyl)-2-methoxybenzene-1-sulfonamide |
| Tamsulosin Hydrochloride-017 | 754930-54-6 | 5-(2-{[2-(2-ethoxyphenoxy)ethyl]amino}-1-hydroxypropyl)-2-methoxybenzenesulfonamide |
| Tamsulosin Hydrochloride-018 | 760126-31-6 | 5-(1-chloro-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl)-2-methoxybenzene-1-sulfonamide |
OptimisedRoute 3Steps 4 · Total yield 18g(Tamsulosin Hydrochloride (API))
Tamsulosin Hydrochloride-019112101-81-2Tamsulosin Hydrochloride-020100-52-7Tamsulosin Hydrochloride-021123-11-5Tamsulosin Hydrochloride-022123-08-0Tamsulosin Hydrochloride-023459-57-4Tamsulosin Hydrochloride-024—Tamsulosin Hydrochloride-025—Tamsulosin Hydrochloride-026—Tamsulosin Hydrochloride-027—Tamsulosin Hydrochloride-028663950-33-2Tamsulosin Hydrochloride-029—Tamsulosin Hydrochloride-030—Tamsulosin Hydrochloride-031663950-41-2Tamsulosin Hydrochloride-032—Tamsulosin Hydrochloride-008106133-20-4API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-019 | 112101-81-2 | 5-(2(R)-Aminopropyl)-2-methoxybenzenesulfonamide |
| Tamsulosin Hydrochloride-020 | 100-52-7Available | Benzaldehyde |
| Tamsulosin Hydrochloride-021 | 123-11-5 | 4-Methoxybenzaldehyde |
| Tamsulosin Hydrochloride-022 | 123-08-0Available | 4-Formylphenol |
| Tamsulosin Hydrochloride-023 | 459-57-4 | (4-Fluorophenyl)methanone |
| Tamsulosin Hydrochloride-024 | - | 2-methoxy-5-[(2R)-2-[(E)-(phenylmethylidene)amino]propyl]benzene-1-sulfonamide |
| Tamsulosin Hydrochloride-025 | - | 2-Methoxy-5-[(2R)-2-[(E)-[(4-methoxyphenyl)methylidene]amino]propyl]benzene-1-sulfonamide |
| Tamsulosin Hydrochloride-026 | - | 5-[(2R)-2-[(E)-[(4-Hydroxyphenyl)methylidene]amino]propyl]-2-methoxybenzene-1-sulfonamide |
| Tamsulosin Hydrochloride-027 | - | 5-[(2R)-2-[(E)-[(4-Fluorophenyl)methylidene]amino]propyl]-2-methoxybenzene-1-sulfonamide |
| Tamsulosin Hydrochloride-028 | 663950-33-2 | 1-ethoxy-2-(2-iodoethoxy)benzene |
| Tamsulosin Hydrochloride-029 | - | (E)-[2-(2-ethoxyphenoxy)ethyl][(2R)-1-(4-methoxy-3-sulfamoylphenyl)propan-2-yl](phenylmethylidene)azanium iodide |
| Tamsulosin Hydrochloride-030 | - | (2R)-N-[2-(2-Ethoxyphenoxy)ethyl]-N-[(E)-(4-methoxyphenyl)methylidene]-1-(4-methoxy-3-sulfamoylphenyl)propan-2-iminium iodide |
| Tamsulosin Hydrochloride-031 | 663950-41-2 | (2R)-N-[2-(2-Ethoxyphenoxy)ethyl]-N-[(E)-(4-hydroxyphenyl)methylidene]-1-(4-methoxy-3-sulfamoylphenyl)propan-2-iminium iodide |
| Tamsulosin Hydrochloride-032 | - | (2R)-N-[2-(2-Ethoxyphenoxy)ethyl]-N-[(E)-(4-fluorophenyl)methylidene]-1-(4-methoxy-3-sulfamoylphenyl)propan-2-iminium iodide |
| Tamsulosin Hydrochloride-008 | 106133-20-4 | (-)-5-[2(R)-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide |
OptimisedRoute 4Steps 2 · Total yield 20.4g(Tamsulosin (Free))
Tamsulosin Hydrochloride-0123250-73-5Tamsulosin Hydrochloride-033169506-15-4Tamsulosin Hydrochloride-019112101-81-2API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-012 | 3250-73-5 | 2-(2-Ethoxyphenoxy)ethanol |
| Tamsulosin Hydrochloride-033 | 169506-15-4 | 2-(2-Ethoxyphenoxy)ethyl mesylate |
| Tamsulosin Hydrochloride-019 | 112101-81-2 | 5-(2(R)-Aminopropyl)-2-methoxybenzenesulfonamide |
OptimisedRoute 6Steps 6 · Total yield /
Tamsulosin Hydrochloride-001122-84-9Tamsulosin Hydrochloride-0023886-69-9Tamsulosin Hydrochloride-040140173-30-4Tamsulosin Hydrochloride-041890708-65-3Tamsulosin Hydrochloride-0093259-03-8Tamsulosin Hydrochloride-042890708-67-5Tamsulosin Hydrochloride-043890708-68-6API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-001 | 122-84-9 | 1-(4-Methoxyphenyl)-2-propanone |
| Tamsulosin Hydrochloride-002 | 3886-69-9Available | (R)-(-)-1-Phenylethylamine |
| Tamsulosin Hydrochloride-040 | 140173-30-4 | 1-(4-Methoxyphenyl)-N-[1(R)-phenylethyl]propan-2(R)-amine |
| Tamsulosin Hydrochloride-041 | 890708-65-3 | 5-[(2R)-2-aminopropyl]-2-methoxybenzene-1-sulfonic acid |
| Tamsulosin Hydrochloride-009 | 3259-03-8 | 1-(2-Bromoethoxy)-2-ethoxybenzene |
| Tamsulosin Hydrochloride-042 | 890708-67-5 | 5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzene-1-sulfonic acid |
| Tamsulosin Hydrochloride-043 | 890708-68-6 | 5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonyl chloride |
OptimisedRoute 7Steps 14 · Total yield 2.091g(Tamsulosin Hydrochloride (API))
Tamsulosin Hydrochloride-04460-18-4Tamsulosin Hydrochloride-045537-55-3Tamsulosin Hydrochloride-046840-97-1Tamsulosin Hydrochloride-04735061-31-5Tamsulosin Hydrochloride-048855594-70-6Tamsulosin Hydrochloride-04986073-42-9Tamsulosin Hydrochloride-05037629-51-9Tamsulosin Hydrochloride-051128224-95-3Tamsulosin Hydrochloride-05269390-34-7Tamsulosin Hydrochloride-053112101-74-3Tamsulosin Hydrochloride-019112101-81-2Tamsulosin Hydrochloride-054916889-79-7Tamsulosin Hydrochloride-008106133-20-4Tamsulosin Hydrochloride-01094-71-3Tamsulosin Hydrochloride-055107-07-3Tamsulosin Hydrochloride-0123250-73-5API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-044 | 60-18-4 | (-)-alpha-Amino-p-hydroxyhydrocinnamic acid |
| Tamsulosin Hydrochloride-045 | 537-55-3 | N-Acetyl-L-tyrosine |
| Tamsulosin Hydrochloride-046 | 840-97-1 | Ethyl N-acetyl-L-tyrosinate |
| Tamsulosin Hydrochloride-047 | 35061-31-5 | Ethyl N-acetyl-O-methyl-L-tyrosinate |
| Tamsulosin Hydrochloride-048 | 855594-70-6 | N-[(2S)-1-Hydroxy-3-(4-methoxyphenyl)propan-2-yl]acetamide |
| Tamsulosin Hydrochloride-049 | 86073-42-9 | N-[(2R)-1-(4-Methoxyphenyl)propan-2-yl]acetamide |
| Tamsulosin Hydrochloride-050 | 37629-51-9 | 1-Methoxy-4-[(1E)-2-nitroprop-1-en-1-yl]benzene |
| Tamsulosin Hydrochloride-051 | 128224-95-3 | N-Hydroxy-1-(4-methoxyphenyl)propan-2-imine |
| Tamsulosin Hydrochloride-052 | 69390-34-7 | N-[(1E)-1-(4-Methoxyphenyl)prop-1-en-2-yl]acetamide |
| Tamsulosin Hydrochloride-053 | 112101-74-3 | N-[(2R)-1-(4-Methoxy-3-sulfamoylphenyl)propan-2-yl]acetamide |
| Tamsulosin Hydrochloride-019 | 112101-81-2 | 5-(2(R)-Aminopropyl)-2-methoxybenzenesulfonamide |
| Tamsulosin Hydrochloride-054 | 916889-79-7 | 2-(2-Ethoxyphenoxy)ethyl 4-methylbenzenesulfonate |
| Tamsulosin Hydrochloride-008 | 106133-20-4 | (-)-5-[2(R)-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide |
| Tamsulosin Hydrochloride-010 | 94-71-3 | 1-Hydroxy-2-ethoxybenzene |
| Tamsulosin Hydrochloride-055 | 107-07-3 | 1-Chloro-2-hydroxyethane |
| Tamsulosin Hydrochloride-012 | 3250-73-5 | 2-(2-Ethoxyphenoxy)ethanol |
OptimisedRoute 8Steps 2 · Total yield 3.28g(Tamsulosin (Free))
Tamsulosin Hydrochloride-0562323018-39-7Tamsulosin Hydrochloride-057—Tamsulosin Hydrochloride-0093259-03-8API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-056 | 2323018-39-7 | 5-(2-aminopropyl)-2-ethoxybenzenesulfonamide |
| Tamsulosin Hydrochloride-057 | - | 5-[(2R)-2-aminopropyl]-2-ethoxybenzene-1-sulfonamide |
| Tamsulosin Hydrochloride-009 | 3259-03-8 | 1-(2-Bromoethoxy)-2-ethoxybenzene |
OptimisedRoute 9Steps 5 · Total yield 46.28gTamsulosin Hydrochloride (API)
Tamsulosin Hydrochloride-058116091-63-5Tamsulosin Hydrochloride-0023886-69-9Tamsulosin Hydrochloride-006116091-64-6Tamsulosin Hydrochloride-019112101-81-2Tamsulosin Hydrochloride-005112101-75-4Tamsulosin Hydrochloride-0093259-03-8Tamsulosin Hydrochloride-008106133-20-4Tamsulosin Hydrochloride-033169506-15-4API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-058 | 116091-63-5 | 2-Methoxy-5-(2-oxopropyl)benzene-1-sulfonamide |
| Tamsulosin Hydrochloride-002 | 3886-69-9Available | (R)-(-)-1-Phenylethylamine |
| Tamsulosin Hydrochloride-006 | 116091-64-6 | 2-Methoxy-5-[(2R)-2-[[(1R)-1-phenylethyl]amino]propyl]benzenesulfonamide hydrochloride |
| Tamsulosin Hydrochloride-019 | 112101-81-2 | 5-(2(R)-Aminopropyl)-2-methoxybenzenesulfonamide |
| Tamsulosin Hydrochloride-005 | 112101-75-4 | 5-[(2R)-2-Aminopropyl]-2-methoxybenzenesulfonamide hydrochloride |
| Tamsulosin Hydrochloride-009 | 3259-03-8 | 1-(2-Bromoethoxy)-2-ethoxybenzene |
| Tamsulosin Hydrochloride-008 | 106133-20-4 | (-)-5-[2(R)-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide |
| Tamsulosin Hydrochloride-033 | 169506-15-4 | 2-(2-Ethoxyphenoxy)ethyl mesylate |
OptimisedRoute 10Steps 6 · Total yield 80g（Tamsulosin Hydrochloride (API)）
Tamsulosin Hydrochloride-05958993-79-6Tamsulosin Hydrochloride-06079-04-9Tamsulosin Hydrochloride-036896468-68-1Tamsulosin Hydrochloride-037896468-69-2Tamsulosin Hydrochloride-038855298-56-5Tamsulosin Hydrochloride-01094-71-3Tamsulosin Hydrochloride-039133261-17-3Tamsulosin Hydrochloride-008106133-20-4API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-059 | 58993-79-6 | (-)-2-(4-Methoxyphenyl)-1-methylethanamine |
| Tamsulosin Hydrochloride-060 | 79-04-9Available | 2-Chloranylethanoyl chloride |
| Tamsulosin Hydrochloride-036 | 896468-68-1 | 2-chloro-N-[(2R)-1-(4-methoxyphenyl)propan-2-yl]acetamide |
| Tamsulosin Hydrochloride-037 | 896468-69-2 | 5-[(2R)-2-(2-chloroacetamido)propyl]-2-methoxybenzene-1-sulfonyl chloride |
| Tamsulosin Hydrochloride-038 | 855298-56-5 | 2-chloro-N-[(2R)-1-(4-methoxy-3-sulfamoylphenyl)propan-2-yl]acetamide |
| Tamsulosin Hydrochloride-010 | 94-71-3 | 1-Hydroxy-2-ethoxybenzene |
| Tamsulosin Hydrochloride-039 | 133261-17-3 | 2-(2-ethoxyphenoxy)-N-[(2R)-1-(4-methoxy-3-sulfamoylphenyl)propan-2-yl]acetamide |
| Tamsulosin Hydrochloride-008 | 106133-20-4 | (-)-5-[2(R)-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide |
OptimisedRoute 11Steps 3 · Total yield 20g(Tamsulosin Hydrochloride-065)
Tamsulosin Hydrochloride-01094-71-3Tamsulosin Hydrochloride-061107-06-2Tamsulosin Hydrochloride-06256842-04-7Tamsulosin Hydrochloride-0631074-82-4Tamsulosin Hydrochloride-064153334-07-7Tamsulosin Hydrochloride-0656781-17-5API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-010 | 94-71-3 | 1-Hydroxy-2-ethoxybenzene |
| Tamsulosin Hydrochloride-061 | 107-06-2 | 1,2-Dichloroethane |
| Tamsulosin Hydrochloride-062 | 56842-04-7 | 1-(2-Chloroethoxy)-2-ethoxybenzene |
| Tamsulosin Hydrochloride-063 | 1074-82-4 | 1,3-Dihydro-1,3-dioxoisoindole potassium salt |
| Tamsulosin Hydrochloride-064 | 153334-07-7 | 2-[2-(2-Ethoxyphenoxy)ethyl]-1H-isoindole-1,3(2H)-dione |
| Tamsulosin Hydrochloride-065 | 6781-17-5 | 2-(2-Ethoxyphenoxy)ethylamine |
OptimisedRoute 12Steps 11 · Total yield /
Tamsulosin Hydrochloride-021123-11-5Tamsulosin Hydrochloride-066543-24-8Tamsulosin Hydrochloride-067711015-29-1Tamsulosin Hydrochloride-068646035-04-3Tamsulosin Hydrochloride-06928047-05-4Tamsulosin Hydrochloride-0706230-11-1Tamsulosin Hydrochloride-07117193-43-0Tamsulosin Hydrochloride-072115424-04-9Tamsulosin Hydrochloride-073115424-05-0Tamsulosin Hydrochloride-074115424-06-1Tamsulosin Hydrochloride-075115424-07-2Tamsulosin Hydrochloride-076115424-09-4API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-021 | 123-11-5 | 4-Methoxybenzaldehyde |
| Tamsulosin Hydrochloride-066 | 543-24-8 | 2-Acetamidoacetic acid |
| Tamsulosin Hydrochloride-067 | 711015-29-1 | (4E)-4-(4-Methoxybenzylidene)-2-methyl-1,3-oxazol-5(4H)-one |
| Tamsulosin Hydrochloride-068 | 646035-04-3 | (2E)-2-(Acetylamino)-3-(4-methoxyphenyl)prop-2-enoic acid |
| Tamsulosin Hydrochloride-069 | 28047-05-4 | N-Acetyl-O-methyl-L-tyrosine |
| Tamsulosin Hydrochloride-070 | 6230-11-1 | O-Methyl-L-tyrosine |
| Tamsulosin Hydrochloride-071 | 17193-43-0 | Ethyl O-methyl-L-tyrosinate |
| Tamsulosin Hydrochloride-072 | 115424-04-9 | Ethyl N-[(benzyloxy)carbonyl]-O-methyl-L-tyrosinate |
| Tamsulosin Hydrochloride-073 | 115424-05-0 | Benzyl [(2S)-1-hydroxy-3-(4-methoxyphenyl)propan-2-yl]carbamate |
| Tamsulosin Hydrochloride-074 | 115424-06-1 | (2S)-2-[[(Benzyloxy)carbonyl]amino]-3-(4-methoxyphenyl)propyl 4-methylbenzenesulfonate |
| Tamsulosin Hydrochloride-075 | 115424-07-2 | Benzyl [(2S)-1-iodo-3-(4-methoxyphenyl)propan-2-yl]carbamate |
| Tamsulosin Hydrochloride-076 | 115424-09-4 | Benzyl [(2R)-1-(4-methoxyphenyl)propan-2-yl]carbamate |
OptimisedRoute 13Steps 5 · Total yield /
Tamsulosin Hydrochloride-077181132-60-5Tamsulosin Hydrochloride-058116091-63-5Tamsulosin Hydrochloride-07891-00-9Tamsulosin Hydrochloride-079—Tamsulosin Hydrochloride-08018531-94-7Tamsulosin Hydrochloride-08165355-14-8Tamsulosin Hydrochloride-082—Tamsulosin Hydrochloride-08335794-11-7API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-077 | 181132-60-5 | (4-Methoxy-3-sulfamoylphenyl)acetic acid |
| Tamsulosin Hydrochloride-058 | 116091-63-5 | 2-Methoxy-5-(2-oxopropyl)benzene-1-sulfonamide |
| Tamsulosin Hydrochloride-078 | 91-00-9 | 1,1-Diphenylmethylamine |
| Tamsulosin Hydrochloride-079 | - | 5-[(2R)-2-[(Diphenylmethyl)amino]propyl]-2-methoxybenzene-1-sulfonamide |
| Tamsulosin Hydrochloride-080 | 18531-94-7 | (+)-2,2'-Dihydroxy-1,1'-dinaphthyl |
| Tamsulosin Hydrochloride-081 | 65355-14-8 | (aR)-5,5',6,6',7,7',8,8'-Octahydro[1,1'-binaphthalene]-2,2'-diol |
| Tamsulosin Hydrochloride-082 | - | (aR)-4-Chloro-8,9,10,11,12,13,14,15-octahydro-4H-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine |
| Tamsulosin Hydrochloride-083 | 35794-11-7 | 3,5-Dimethylpiperidine |
OptimisedRoute 14Steps 6 · Total yield /
Tamsulosin Hydrochloride-08485276-46-6Tamsulosin Hydrochloride-0656781-17-5Tamsulosin Hydrochloride-085—Tamsulosin Hydrochloride-086873442-10-5Tamsulosin Hydrochloride-08715761-39-4Tamsulosin Hydrochloride-088541-41-3Tamsulosin Hydrochloride-0891392268-76-6Tamsulosin Hydrochloride-0905834-17-3Tamsulosin Hydrochloride-0911096141-21-7Tamsulosin Hydrochloride-0921096141-19-3API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-084 | 85276-46-6 | 5-Acetyl-2-methoxybenzene-1-sulfonamide |
| Tamsulosin Hydrochloride-065 | 6781-17-5 | 2-(2-Ethoxyphenoxy)ethylamine |
| Tamsulosin Hydrochloride-085 | - | - |
| Tamsulosin Hydrochloride-086 | 873442-10-5 | (2R)-Hydroxy(phenyl)acetic acid 5-[(2R)-2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzene-1-sulfonamide |
| Tamsulosin Hydrochloride-087 | 15761-39-4 | (S)-1-(tert-Butoxycarbonyl)pyrrolidine-2-carboxylic acid |
| Tamsulosin Hydrochloride-088 | 541-41-3 | Carbonochloridic acid ethyl ester |
| Tamsulosin Hydrochloride-089 | 1392268-76-6 | Ethoxycarbonyl 1-(tert-butoxycarbonyl)-L-prolinate |
| Tamsulosin Hydrochloride-090 | 5834-17-3 | 2-Methoxydibenzo[b,d]furan-3-amine |
| Tamsulosin Hydrochloride-091 | 1096141-21-7 | tert-Butyl (2S)-2-[(2-methoxydibenzo[b,d]furan-3-yl)carbamoyl]pyrrolidine-1-carboxylate |
| Tamsulosin Hydrochloride-092 | 1096141-19-3 | N-(2-Methoxydibenzo[b,d]furan-3-yl)-L-prolinamide |
OptimisedRoute 15Steps 6 · Total yield /
Tamsulosin Hydrochloride-001122-84-9Tamsulosin Hydrochloride-0023886-69-9Tamsulosin Hydrochloride-0932077235-60-8Tamsulosin Hydrochloride-040140173-30-4Tamsulosin Hydrochloride-05958993-79-6Tamsulosin Hydrochloride-094146374-27-8Tamsulosin Hydrochloride-0952077235-62-0Tamsulosin Hydrochloride-096—API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-001 | 122-84-9 | 1-(4-Methoxyphenyl)-2-propanone |
| Tamsulosin Hydrochloride-002 | 3886-69-9Available | (R)-(-)-1-Phenylethylamine |
| Tamsulosin Hydrochloride-093 | 2077235-60-8 | (2E)-1-(4-Methoxyphenyl)-N-[(1R)-1-phenylethyl]propan-2-imine |
| Tamsulosin Hydrochloride-040 | 140173-30-4 | 1-(4-Methoxyphenyl)-N-[1(R)-phenylethyl]propan-2(R)-amine |
| Tamsulosin Hydrochloride-059 | 58993-79-6 | (-)-2-(4-Methoxyphenyl)-1-methylethanamine |
| Tamsulosin Hydrochloride-094 | 146374-27-8 | (+/-)-tert-Butyl sulfinamide |
| Tamsulosin Hydrochloride-095 | 2077235-62-0 | (SR)-N-[(2E)-1-(4-Methoxyphenyl)propan-2-ylidene]-2-methylpropane-2-sulfinamide |
| Tamsulosin Hydrochloride-096 | - | (SR)-N-[(2R)-1-(4-Methoxyphenyl)propan-2-yl]-2-methylpropane-2-sulfinamide |
OptimisedRoute 16Steps 3 · Total yield 10.4g(Tamsulosin Hydrochloride (API))
Tamsulosin Hydrochloride-006116091-64-6Tamsulosin Hydrochloride-0093259-03-8Tamsulosin Hydrochloride-0971076263-86-9Tamsulosin Hydrochloride-008106133-20-4API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-006 | 116091-64-6 | 2-Methoxy-5-[(2R)-2-[[(1R)-1-phenylethyl]amino]propyl]benzenesulfonamide hydrochloride |
| Tamsulosin Hydrochloride-009 | 3259-03-8 | 1-(2-Bromoethoxy)-2-ethoxybenzene |
| Tamsulosin Hydrochloride-097 | 1076263-86-9 | 5-[(2R)-2-[[2-(2-Ethoxyphenoxy)ethyl][(1R)-1-phenylethyl]amino]propyl]-2-methoxybenzene-1-sulfonamide |
| Tamsulosin Hydrochloride-008 | 106133-20-4 | (-)-5-[2(R)-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide |
OptimisedRoute 17Steps 9 · Total yield /
Tamsulosin Hydrochloride-098104-01-8Tamsulosin Hydrochloride-001122-84-9Tamsulosin Hydrochloride-0997790-94-5Tamsulosin Hydrochloride-10080223-79-6Tamsulosin Hydrochloride-10175-64-9Tamsulosin Hydrochloride-1022761700-43-8Tamsulosin Hydrochloride-0023886-69-9Tamsulosin Hydrochloride-1032761700-44-9Tamsulosin Hydrochloride-1042761700-42-7Tamsulosin Hydrochloride-1056781-16-4Tamsulosin Hydrochloride-01094-71-3Tamsulosin Hydrochloride-106107-14-2Tamsulosin Hydrochloride-1072761700-45-0Tamsulosin Hydrochloride-008106133-20-4API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-098 | 104-01-8 | (4-Methoxyphenyl)acetic acid |
| Tamsulosin Hydrochloride-001 | 122-84-9 | 1-(4-Methoxyphenyl)-2-propanone |
| Tamsulosin Hydrochloride-099 | 7790-94-5 | Chloridosulfuric acid |
| Tamsulosin Hydrochloride-100 | 80223-79-6 | 2-Methoxy-5-(2-oxopropyl)benzene-1-sulfonyl chloride |
| Tamsulosin Hydrochloride-101 | 75-64-9Available | 1,1-Dimethylethylamine |
| Tamsulosin Hydrochloride-102 | 2761700-43-8 | N-tert-Butyl-2-methoxy-5-(2-oxopropyl)benzene-1-sulfonamide |
| Tamsulosin Hydrochloride-002 | 3886-69-9Available | (R)-(-)-1-Phenylethylamine |
| Tamsulosin Hydrochloride-103 | 2761700-44-9 | N-tert-Butyl-2-methoxy-5-[(2R)-2-[[(1R)-1-phenylethyl]amino]propyl]benzene-1-sulfonamide |
| Tamsulosin Hydrochloride-104 | 2761700-42-7 | 5-[(2R)-2-Aminopropyl]-N-tert-butyl-2-methoxybenzene-1-sulfonamide |
| Tamsulosin Hydrochloride-105 | 6781-16-4 | (2-Ethoxyphenoxy)acetonitrile |
| Tamsulosin Hydrochloride-010 | 94-71-3 | 1-Hydroxy-2-ethoxybenzene |
| Tamsulosin Hydrochloride-106 | 107-14-2Available | 2-Chloroacetonitrile |
| Tamsulosin Hydrochloride-107 | 2761700-45-0 | N-tert-Butyl-5-[(2R)-2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzene-1-sulfonamide |
| Tamsulosin Hydrochloride-008 | 106133-20-4 | (-)-5-[2(R)-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide |
OptimisedRoute 18Steps 7 · Total yield 165g(Racemic Tamsulosinc (Free))
Tamsulosin Hydrochloride-01196-49-1Tamsulosin Hydrochloride-01094-71-3Tamsulosin Hydrochloride-0123250-73-5Tamsulosin Hydrochloride-033169506-15-4Tamsulosin Hydrochloride-108107-21-1Tamsulosin Hydrochloride-1094672-49-5Tamsulosin Hydrochloride-1102761700-47-2Tamsulosin Hydrochloride-1022761700-43-8Tamsulosin Hydrochloride-1112761700-48-3Tamsulosin Hydrochloride-11294666-07-6API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-011 | 96-49-1 | 1,3-Dioxolan-2-one |
| Tamsulosin Hydrochloride-010 | 94-71-3 | 1-Hydroxy-2-ethoxybenzene |
| Tamsulosin Hydrochloride-012 | 3250-73-5 | 2-(2-Ethoxyphenoxy)ethanol |
| Tamsulosin Hydrochloride-033 | 169506-15-4 | 2-(2-Ethoxyphenoxy)ethyl mesylate |
| Tamsulosin Hydrochloride-108 | 107-21-1Available | 1,2-Dihydroxyethane |
| Tamsulosin Hydrochloride-109 | 4672-49-5 | 1,2-Dimethylsulfonyloxyethane |
| Tamsulosin Hydrochloride-110 | 2761700-47-2 | 5-(2-Aminopropyl)-N-tert-butyl-2-methoxybenzene-1-sulfonamide |
| Tamsulosin Hydrochloride-102 | 2761700-43-8 | N-tert-Butyl-2-methoxy-5-(2-oxopropyl)benzene-1-sulfonamide |
| Tamsulosin Hydrochloride-111 | 2761700-48-3 | (±)-N-tert-Butyl-5-(2-[[2-(2-ethoxyphenoxy)ethyl]amino]propyl)-2-methoxybenzene-1-sulfonamide |
| Tamsulosin Hydrochloride-112 | 94666-07-6 | (±)-5-(2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl)-2-methoxybenzene-1-sulfonamide |
OptimisedRoute 20Steps 3 · Total yield 18.5g(Tamsulosin Hydrochloride-059)
Tamsulosin Hydrochloride-119126395-29-7Tamsulosin Hydrochloride-1202575821-58-6Tamsulosin Hydrochloride-121167421-85-4Tamsulosin Hydrochloride-05958993-79-6API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-119 | 126395-29-7 | tert-Butyl [(2S)-1-hydroxy-3-(4-methoxyphenyl)propan-2-yl]carbamate |
| Tamsulosin Hydrochloride-120 | 2575821-58-6 | tert-Butyl (2S)-2-[(4-methoxyphenyl)methyl]aziridine-1-carboxylate |
| Tamsulosin Hydrochloride-121 | 167421-85-4 | tert-Butyl [(2R)-1-(4-methoxyphenyl)propan-2-yl]carbamate |
| Tamsulosin Hydrochloride-059 | 58993-79-6 | (-)-2-(4-Methoxyphenyl)-1-methylethanamine |
OptimisedRoute 21Steps 8 · Total yield /
Tamsulosin Hydrochloride-098104-01-8Tamsulosin Hydrochloride-001122-84-9Tamsulosin Hydrochloride-07891-00-9Tamsulosin Hydrochloride-122—Tamsulosin Hydrochloride-05958993-79-6Tamsulosin Hydrochloride-04986073-42-9Tamsulosin Hydrochloride-08018531-94-7Tamsulosin Hydrochloride-08165355-14-8Tamsulosin Hydrochloride-082—Tamsulosin Hydrochloride-08335794-11-7Tamsulosin Hydrochloride-123591-22-0API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-098 | 104-01-8 | (4-Methoxyphenyl)acetic acid |
| Tamsulosin Hydrochloride-001 | 122-84-9 | 1-(4-Methoxyphenyl)-2-propanone |
| Tamsulosin Hydrochloride-078 | 91-00-9 | 1,1-Diphenylmethylamine |
| Tamsulosin Hydrochloride-122 | - | (2R)-N-(Diphenylmethyl)-1-(4-methoxyphenyl)propan-2-amine |
| Tamsulosin Hydrochloride-059 | 58993-79-6 | (-)-2-(4-Methoxyphenyl)-1-methylethanamine |
| Tamsulosin Hydrochloride-049 | 86073-42-9 | N-[(2R)-1-(4-Methoxyphenyl)propan-2-yl]acetamide |
| Tamsulosin Hydrochloride-080 | 18531-94-7 | (+)-2,2'-Dihydroxy-1,1'-dinaphthyl |
| Tamsulosin Hydrochloride-081 | 65355-14-8 | (aR)-5,5',6,6',7,7',8,8'-Octahydro[1,1'-binaphthalene]-2,2'-diol |
| Tamsulosin Hydrochloride-082 | - | (aR)-4-Chloro-8,9,10,11,12,13,14,15-octahydro-4H-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepine |
| Tamsulosin Hydrochloride-083 | 35794-11-7 | 3,5-Dimethylpiperidine |
| Tamsulosin Hydrochloride-123 | 591-22-0 | 3,5-Dimethylpyridine |
ProcessRoute 5Steps 5 · Total yield 1.84kg(Tamsulosin (Free))
Tamsulosin Hydrochloride-03464-13-1Tamsulosin Hydrochloride-035105-39-5Tamsulosin Hydrochloride-036896468-68-1Tamsulosin Hydrochloride-037896468-69-2Tamsulosin Hydrochloride-038855298-56-5Tamsulosin Hydrochloride-01094-71-3Tamsulosin Hydrochloride-039133261-17-3API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-034 | 64-13-1 | (+-)-1-(p-Methoxyphenyl)-2-aminopropane |
| Tamsulosin Hydrochloride-035 | 105-39-5 | Ethyl 2-chloroacetate |
| Tamsulosin Hydrochloride-036 | 896468-68-1 | 2-chloro-N-[(2R)-1-(4-methoxyphenyl)propan-2-yl]acetamide |
| Tamsulosin Hydrochloride-037 | 896468-69-2 | 5-[(2R)-2-(2-chloroacetamido)propyl]-2-methoxybenzene-1-sulfonyl chloride |
| Tamsulosin Hydrochloride-038 | 855298-56-5 | 2-chloro-N-[(2R)-1-(4-methoxy-3-sulfamoylphenyl)propan-2-yl]acetamide |
| Tamsulosin Hydrochloride-010 | 94-71-3 | 1-Hydroxy-2-ethoxybenzene |
| Tamsulosin Hydrochloride-039 | 133261-17-3 | 2-(2-ethoxyphenoxy)-N-[(2R)-1-(4-methoxy-3-sulfamoylphenyl)propan-2-yl]acetamide |
ProcessRoute 19Steps 4 · Total yield 25.51kg(Tamsulosin Hydrochloride (API))
Tamsulosin Hydrochloride-11339684-80-5Tamsulosin Hydrochloride-11471999-74-1Tamsulosin Hydrochloride-01094-71-3Tamsulosin Hydrochloride-115—Tamsulosin Hydrochloride-0656781-17-5Tamsulosin Hydrochloride-116—Tamsulosin Hydrochloride-117—Tamsulosin Hydrochloride-118—API · Tamsulosin Hydrochloride
| Code | CAS No. | Intermediate |
|---|---|---|
| Tamsulosin Hydrochloride-113 | 39684-80-5 | 2-(Boc-Amino)ethyl bromide |
| Tamsulosin Hydrochloride-114 | 71999-74-1 | tert-Butyl (2-chloroethyl)carbamate |
| Tamsulosin Hydrochloride-010 | 94-71-3 | 1-Hydroxy-2-ethoxybenzene |
| Tamsulosin Hydrochloride-115 | - | N-Boc-2-(2-ethoxyphenoxy)ethanamine |
| Tamsulosin Hydrochloride-065 | 6781-17-5 | 2-(2-Ethoxyphenoxy)ethylamine |
| Tamsulosin Hydrochloride-116 | - | (2S)-1-(4-Methoxy-3-sulfamoylphenyl)propan-2-yl methanesulfonate |
| Tamsulosin Hydrochloride-117 | - | (2S)-1-(4-Methoxy-3-sulfamoylphenyl)propan-2-yl trifluoroacetate |
| Tamsulosin Hydrochloride-118 | - | 5-[(2S)-2-Hydroxypropyl]-2-methoxybenzene-1-sulfonamide |
Frequently asked questions
What are the approved indications of Tamsulosin Hydrochloride?
Approved indications include: Benign prostatic hyperplasia.
When does the Tamsulosin Hydrochloride patent expire?
No public expiry year is available for Tamsulosin Hydrochloride yet; this page updates once verified.
How many synthesis routes are recorded for Tamsulosin Hydrochloride?
21 synthesis routes are recorded; the shortest is 2 steps with 20.4g(Tamsulosin (Free)) total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Tamsulosin Hydrochloride intermediates?
7 intermediate CAS of Tamsulosin Hydrochloride are available through the Unibest supply network — see the route tables on this page and request a quote per CAS.
How do I get a quote for Tamsulosin Hydrochloride intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29