Ibuprofen
Tier C — Watch / tradeIbuprofen
Targets：COXs
Brand：Ibuprox, CDT-<span class="highlightText">ibuprofen</span>, OXPzero <span class="highlightText">ibuprofen</span>, Dorifen, Spedifen, Algifor Junior, Dolgit, Flarin, Amelior, Brufen Retard, Nurofen Meltlets, Motrin, Aktren, Advil, Brufen, Intrafen, Caldolor, Pedea
Indications (approved)：Fever, Arthritis, Pain, Patent ductus arteriosus, Pharyngitis, Influenza virus infection, Musculoskeletal pain, Back pain
Regional status
Factories producing this API1
Factories registered as producing this API in our sourcing network (RFQ records + product master), sorted by RFQ activity; the snapshot carries no cost or customer data.
1 producing factories on file — sign in to view the named list (factory details are not shown to guests).
Sign in to view factories →Synthetic routes & intermediates4 routes
Routes are ordered originator first, then optimised / process (non-patent) routes; each lists steps, overall yield and the intermediate table (code / CAS / name) — ready for supplier sourcing and RFQ. Rendered by this site from structured data; no third-party route graphics used.
| Code | CAS No. | Intermediate |
|---|---|---|
| IBUP-001 | 36039-36-8 | 2-(4-isobutylphenyl)propan-1-ol |
| Ibuprofen | 15687-27-1 | 2-(4-isobutylphenyl)propanoic acid |
| Code | CAS No. | Intermediate |
|---|---|---|
| IBUP-002 | 38861-78-8 | 1-(4-isobutylphenyl)ethan-1-one |
| IBUP-003 | 34352-86-8 | 1-isobutyl-4-(prop-1-en-2-yl)benzene |
| IBUP-004 | 1424343-26-9 | 2-(4-isobutylphenyl)prop-2-en-1-ol |
| IBUP-005 | 51407-46-6 | 2-(4-isobutylphenyl)propanal |
| Code | CAS No. | Intermediate |
|---|---|---|
| IBUP-006 | 80336-64-7 | 2-bromo-1-(4-isobutylphenyl)propan-1-one |
| IBUP-007 | 126-30-7 | 2,2-dimethylpropane-1,3-diol |
| Code | CAS No. | Intermediate |
|---|---|---|
| IBUP-008 | 538-93-2 | isobutylbenzene |
| IBUP-009 | 40150-92-3 | 1-(4-isobutylphenyl)ethan-1-ol |
| IBUP-010 | 1186634-35-4 | 1-(4-isobutylphenyl)ethyl methanesulfonate |
| IBUP-011 | 58609-73-7 | 2-(4-isobutylphenyl)propanenitrile |
Frequently asked questions
What are the approved indications of Ibuprofen?
Approved indications include: Fever, Arthritis, Pain, Patent ductus arteriosus, Pharyngitis, Influenza virus infection, Musculoskeletal pain, Back pain.
When does the Ibuprofen patent expire?
No public expiry year is available for Ibuprofen yet; this page updates once verified.
How many synthesis routes are recorded for Ibuprofen?
4 synthesis routes are recorded; the shortest is 1 steps with / total yield. Intermediates in each route carry codes and CAS numbers.
Where can I buy Ibuprofen intermediates?
All intermediates in Ibuprofen routes have CAS profiles — you can submit an RFQ per CAS and it enters the Unibest matching pool.
How do I get a quote for Ibuprofen intermediates?
Open the CAS profile of the target intermediate from this page, or submit an RFQ directly — the CAS enters the matching flow automatically and the supply network responds with quotes.
Source: cross-verified data (structured fields only) · 2026-09-29