Unibest
← Back to patent-cliff list

CAS 1004300-76-8

2-(1-Hydroxycyclohexyl)-2-(4-hydroxyphenyl)-N,N-dimethylacetamide

Codes: Desvenlafaxine-016

Application context (from source-drug indications)

Major depressive disorderDesvenlafaxineDepressive disorderDesvenlafaxine

Source drugs (routes using this intermediate)

DrugTierExpiry
DesvenlafaxineTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

DesvenlafaxineOptimised routesteps: 7total yield: 5.8g(Desvenlafaxine (Free))
2-(4-Hydroxyphenyl)acetic acid→2-(4-Hydroxyphenyl)acetyl chloride→Dimethylamine→2-(4-Hydroxyphenyl)-N,N-dimethylacetamide→2-[4-[tert-Butyl(dimethyl)silyloxy]phenyl]-N,N-dimethylacetamide→Cyclohexanone→2-[4-[tert-Butyl(dimethyl)silyloxy]phenyl]-2-(1-hydroxycyclohexyl)-N,N-dimethylacetamide→4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol→2-(1-Hydroxycyclohexyl)-2-(4-hydroxyphenyl)-N,N-dimethylacetamide

Intermediates available on this site

No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.

This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.