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CAS 1006868-73-0
methyl ((S)-1-(((S)-4-chloro-3-oxo-1-phenylbutan-2-yl)amino)-3,3-dimethyl-1-oxobutan-2-yl)carbamate
Codes: ATAZ-018
Application context (from source-drug indications)
HIV infectionAtazanavir Sulfate/CobicistatHIV infectionAtazanavir SulfateAcquired immunodeficiency syndromeAtazanavir SulfateMycobacterium tuberculosis infectionAtazanavir SulfateType 1 diabetesAtazanavir Sulfate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Atazanavir Sulfate/Cobicistat | Tier C — Watch / trade | - |
| Atazanavir Sulfate | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-(pyridin-2-yl)benzaldehyde→(S)-2-((methoxycarbonyl)amino)-3,3-dimethylbutanoic acid→methyl (S)-(1-hydrazinyl-3,3-dimethyl-1-oxobutan-2-yl)carbamate hydrochloride→methyl (S)-(3-methyl-1-oxo-1-(2-(4-(pyridin-2-yl)benzyl)hydrazinyl)butan-2-yl)carbamate→methyl ((S)-1-(((S)-4-chloro-3-oxo-1-phenylbutan-2-yl)amino)-3,3-dimethyl-1-oxobutan-2-yl)carbamate→methyl ((5S,11S,14S)-11-benzyl-5-(tert-butyl)-15,15-dimethyl-3,6,10,13-tetraoxo-8-(4-(pyridin-2-yl)benzyl)-2-oxa-4,7,8,12-tetraazahexadecan-14-yl)carbamate→tert-butyl (S)-(4-chloro-3-oxo-1-phenylbutan-2-yl)carbamate
4-(pyridin-2-yl)benzaldehyde→(S)-2-((methoxycarbonyl)amino)-3,3-dimethylbutanoic acid→methyl (S)-(1-hydrazinyl-3,3-dimethyl-1-oxobutan-2-yl)carbamate hydrochloride→methyl (S)-(3-methyl-1-oxo-1-(2-(4-(pyridin-2-yl)benzyl)hydrazinyl)butan-2-yl)carbamate→methyl ((S)-1-(((S)-4-chloro-3-oxo-1-phenylbutan-2-yl)amino)-3,3-dimethyl-1-oxobutan-2-yl)carbamate→methyl ((5S,11S,14S)-11-benzyl-5-(tert-butyl)-15,15-dimethyl-3,6,10,13-tetraoxo-8-(4-(pyridin-2-yl)benzyl)-2-oxa-4,7,8,12-tetraazahexadecan-14-yl)carbamate→tert-butyl (S)-(4-chloro-3-oxo-1-phenylbutan-2-yl)carbamate
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This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.