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CAS 102-92-1
(2E)-3-phenylprop-2-enoyl chloride
Codes: Lercanidipine Hydrochloride-030
Application context (from source-drug indications)
Essential hypertensionValsartan/Lercanidipine HydrochlorideHypertensionLercanidipine Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Valsartan/Lercanidipine Hydrochloride | Tier C — Watch / trade | - |
| Lercanidipine Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
3-Phenyl-2(E)-propenoic acid→(2E)-3-phenylprop-2-enoyl chloride→Methylamine→N-Methyl-3-phenylacrylamide→Benzene→N-Methyl-3,3-diphenylpropanamide→(3,3-Diphenylpropyl)(methyl)amine→1-Chloro-2-methyl-2-propanol→1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methylpropan-2-ol→Methyl 5-[[(diethoxyphosphoryl)oxy]carbonyl]-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate→(+/-)-5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3-pyridinecarboxylic acid
3-Phenyl-2(E)-propenoic acid→(2E)-3-phenylprop-2-enoyl chloride→Methylamine→N-Methyl-3-phenylacrylamide→Benzene→N-Methyl-3,3-diphenylpropanamide→(3,3-Diphenylpropyl)(methyl)amine→1-Chloro-2-methyl-2-propanol→1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methylpropan-2-ol→Methyl 5-[[(diethoxyphosphoryl)oxy]carbonyl]-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate→(+/-)-5-(Methoxycarbonyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydro-3-pyridinecarboxylic acid
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