CAS 103-80-0

2-Phenylacetyl chloride

Codes: LEVO-017, (II)91353-4-a

Application context (from source-drug indications)

Major depressive disorderLevomilnacipran HydrochlorideIschaemic strokeLevomilnacipran HydrochlorideDepressionLevomilnacipran HydrochlorideBack painDiclofenac Sodium/Eperisone HydrochlorideOsteoarthritisDiclofenac SodiumRheumatoid arthritisDiclofenac SodiumAnkylosing spondylitisDiclofenac SodiumCommon bile duct diseaseDiclofenac SodiumDental pulp diseaseDiclofenac SodiumArthritisDiclofenac Sodium

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Levomilnacipran Hydrochloride	Tier C — Watch / trade	-
Diclofenac Sodium/Eperisone Hydrochloride	Tier C — Watch / trade	-
Diclofenac Sodium	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Levomilnacipran HydrochlorideOptimised routesteps: 11total yield: /

(1S,5R)-1-phenyl-3-oxabicyclo[3.1.0]hexan-2-one→LEVO-009→LEVO-016→LEVO-017→LEVO-018→LEVO-019→LEVO-020→LEVO-021→LEVO-022→LEVO-023→LEVO-024→LEVO-025→LEVO-026

Diclofenac Sodium/Eperisone HydrochlorideOptimised routesteps: 4total yield: /

2,6-Dichloroaniline→2-Phenylacetyl chloride→N-(2,6-Dichlorophenyl)-2-phenylacetamide→N-Chloro-N-(2,6-dichlorophenyl)-2-phenylacetamide→1-(2,6-Dichlorophenyl)-2,3-dihydro-1H-indol-2-one→2-Chloro-N-(2,6-dichlorophenyl)-N-phenylacetamide

Diclofenac SodiumOptimised routesteps: 4total yield: /

Intermediates available on this site

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