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CAS 1031767-71-1
(S)-3-chloro-N-((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-N-methylpropan-1-amine
Codes: IVAB-030
Application context (from source-drug indications)
Heart failureIvabradine HydrochlorideAngina pectorisIvabradine HydrochlorideCardiogenic shockIvabradine HydrochlorideIschaemic heart diseaseIvabradine HydrochlorideStable anginaIvabradine HydrochlorideLymphomaIvabradine Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Ivabradine Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-(3,4-dimethoxyphenyl)ethanamine→tert-butyl (3,4-dimethoxyphenethyl)carbamate→(S)-3-chloro-N-((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-N-methylpropan-1-amine→tert-butyl (S)-(3-(((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)(3,4-dimethoxyphenethyl)carbamate→(S)-N1-((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)-N3-(3,4-dimethoxyphenethyl)-N1-methylpropane-1,3-diamine→(S)-2-((3-(((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)(3,4-dimethoxyphenethyl)amino)-2-oxoethyl acetate→(S)-N-(3-(((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-N-(3,4-dimethoxyphenethyl)-2-hydroxyacetamide→(S)-N-(3-(((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-N-(3,4-dimethoxyphenethyl)-2-oxoacetamide→3-(3-((((S)-3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1-(phenylthio)-1,3,4,5-tetrahydro-2H-benzo[d]azepin-2-one
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