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CAS 1041845-96-8

5-(2-cyanopyridin-4-yl)-N,N-dimethyl-3-(pyridin-4-yl)-1H-1,2,4-triazole-1-carboxamide

Codes: TOPI-010

Application context (from source-drug indications)

HyperuricaemiaTopiroxostatGoutTopiroxostatDiabetic nephropathyTopiroxostat

Source drugs (routes using this intermediate)

DrugTierExpiry
TopiroxostatTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

TopiroxostatOptimised routesteps: 4total yield: 29.4 g
4-cyanopyridine 1-oxide→isonicotinohydrazide→dimethylcarbamic chloride→dimethylcarbamic chloride→5-(2-cyanopyridin-4-yl)-N,N-dimethyl-3-(pyridin-4-yl)-1H-1,2,4-triazole-1-carboxamide

Intermediates available on this site

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