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CAS 1064650-21-0
ethyl (Z)-3-(dimethylamino)-2-(5-methyl-3-nitropyridin-2-yl)acrylate
Codes: TBA-7371-005
Application context (from source-drug indications)
Pulmonary tuberculosisTBA-7371Mycobacterium tuberculosis infectionTBA-7371
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| TBA-7371 | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
2-chloro-5-methyl-3-nitropyridine→diethyl malonate→diethyl 2-(5-methyl-3-nitropyridin-2-yl)malonate→ethyl 2-(5-methyl-3-nitropyridin-2-yl)acetate→ethyl (Z)-3-(dimethylamino)-2-(5-methyl-3-nitropyridin-2-yl)acrylate→ethyl 6-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxylate→4-(chloromethyl)-6-methoxy-5-methylpyrimidine→ethyl 1-((6-methoxy-5-methylpyrimidin-4-yl)methyl)-6-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxylate→1-((6-methoxy-5-methylpyrimidin-4-yl)methyl)-6-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxylic acid→N-(2-hydroxyethyl)-1-((6-methoxy-5-methylpyrimidin-4-yl)methyl)-6-methyl-1H-pyrrolo[3,2-b]pyridine-3-carboxamide
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