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CAS 1069115-32-7
tert-butyl (3-(7,8-dimethoxy-2-oxo-1H-benzo[d]azepin-3(2H)-yl)propyl)(methyl)carbamate
Codes: IVAB-011
Application context (from source-drug indications)
Heart failureIvabradine HydrochlorideAngina pectorisIvabradine HydrochlorideCardiogenic shockIvabradine HydrochlorideIschaemic heart diseaseIvabradine HydrochlorideStable anginaIvabradine HydrochlorideLymphomaIvabradine Hydrochloride
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Ivabradine Hydrochloride | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(S)-3-(3-(((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-4,5-dihydro-1H-benzo[d]azepin-2(3H)-one→7,8-dimethoxy-1H-benzo[d]azepin-2(3H)-one→tert-butyl (3-chloropropyl)(methyl)carbamate→tert-butyl (3-(7,8-dimethoxy-2-oxo-1H-benzo[d]azepin-3(2H)-yl)propyl)(methyl)carbamate→7,8-dimethoxy-3-(3-(methylamino)propyl)-1H-benzo[d]azepin-2(3H)-one→7-(iodomethyl)-3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-triene→3-(3-(((3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl)methyl)(methyl)amino)propyl)-7,8-dimethoxy-1H-benzo[d]azepin-2(3H)-one
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