CAS 107-13-1

2-Propenonitrileacrylonitrile

Codes: Molnupiravir-049, CINA-017, Urapidil-021

Application context (from source-drug indications)

COVID-19Molnupiravir呼吸道合胞体病毒感染MolnupiravirInfluenza virus infectionMolnupiravirRenal impairmentMolnupiravirHepatic function declineMolnupiravirHypercalcaemiaCinacalcet HydrochlorideSecondary hyperparathyroidismCinacalcet HydrochlorideHyperparathyroidismCinacalcet HydrochloridePrimary hyperparathyroidismCinacalcet HydrochlorideChronic renal impairmentCinacalcet HydrochlorideCardiogenic oedemaCinacalcet HydrochlorideHypertensionUrapidil hydrochloride

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Molnupiravir	Tier B — Position early	-
Cinacalcet Hydrochloride	Tier B — Position early	-
Urapidil hydrochloride	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

MolnupiravirOptimised routesteps: 3total yield: 245g(Molnupiravir)

3-(2-Oxoazepan-1-yl)propanenitrile→Azepan-2-one→2-Propenonitrile→1-(3-Aminopropyl)azepan-2-one

Cinacalcet HydrochlorideProcess routesteps: 5total yield: 371 g

(R)-1-(naphthalen-1-yl)ethan-1-amine→3-(3-(trifluoromethyl)phenyl)propanoic acid→(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propanamide→3-(trifluoromethyl)aniline→acrylonitrile→2-chloro-3-(3-(trifluoromethyl)phenyl)propanenitrile→2-chloro-3-(3-(trifluoromethyl)phenyl)propanoic acid

Urapidil hydrochlorideOptimised routesteps: 1total yield: 58.9g(Urapidil-022)

1-(2-Methoxyphenyl)piperazine→2-Propenonitrile→3-[4-(2-Methoxyphenyl)piperazin-1-yl]propanenitrile

Intermediates available on this site

Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.

Supplier	Product	Price band	MOQ	Lead time	Qualifications	Action
Unibest Taizhou GMP-like Site	((3aR,4R,6R,6aR)-6-(4-(hydroxyamino)-2-oxopyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl isobutyrate Pharmaceutical Intermediates	On request	On request	On request	—

This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.