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CAS 1070-11-7

(2S,2'S)-2,2'-(Ethane-1,2-diyldiimino)dibutan-1-ol dihydrochloride

Codes: Ethambutol Hydrochloride-004

Application context (from source-drug indications)

Mycobacterium tuberculosis infectionEthambutol Hydrochloride/Rifampicin/IsoniazidPulmonary tuberculosisEthambutol Hydrochloride

Source drugs (routes using this intermediate)

DrugTierExpiry
Ethambutol Hydrochloride/Rifampicin/IsoniazidTier C — Watch / trade-
Ethambutol HydrochlorideTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Ethambutol Hydrochloride/Rifampicin/IsoniazidOptimised routesteps: 2total yield: 27g(Ethambutol dihydrochloride (API))
Methyl L-methioninate→(2S)-2-Aminobutan-1-ol→Glycol dichloride→(2S,2'S)-2,2'-(Ethane-1,2-diyldiimino)dibutan-1-ol dihydrochloride
Ethambutol HydrochlorideOptimised routesteps: 2total yield: 27g(Ethambutol dihydrochloride (API))
Methyl L-methioninate→(2S)-2-Aminobutan-1-ol→Glycol dichloride→(2S,2'S)-2,2'-(Ethane-1,2-diyldiimino)dibutan-1-ol dihydrochloride

Intermediates available on this site

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