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CAS 1092527-68-8
1,2-O-Isopropylidene-6-(methoxycarbonylamino)-3,5,6-trideoxy-alpha-D-erythro-hexofuranose
Codes: Atorvastatin-078
Application context (from source-drug indications)
Cardiac and vascular disordersAtorvastatin/Hydrochlorothiazide/Aspirin/EnalaprilHypertensionAtorvastatin/Hydrochlorothiazide/Aspirin/EnalaprilHyperlipidaemiaAtorvastatin/Hydrochlorothiazide/Aspirin/EnalaprilHeart diseaseAtorvastatin/Hydrochlorothiazide/Aspirin/EnalaprilHyperlipidaemiaAtorvastatin strontiumSubarachnoid haemorrhageAtorvastatin strontiumHypertensionAtorvastatin strontium
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Atorvastatin/Hydrochlorothiazide/Aspirin/Enalapril | Tier C — Watch / trade | - |
| Atorvastatin strontium | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
Ethyl (diethoxyphosphoryl)acetate→3-[(3aR,5S,6aR)-2,2-Dimethylperhydrofuro[2,3-d][1,3]dioxol-5-yl]-2-propenoic acid ethyl ester→3-[(3aR,5R,6aR)-2,2-Dimethylperhydrofuro[2,3-d][1,3]dioxol-5-yl]propionic acid ethyl ester→3-[(3aR,5R,6aR)-2,2-Dimethylperhydrofuro[2,3-d][1,3]dioxol-5-yl]propionamide→1,2-O-Isopropylidene-6-(methoxycarbonylamino)-3,5,6-trideoxy-alpha-D-erythro-hexofuranose→(3aR,5S,6aR)-2,2-Dimethylperhydrofuro[2,3-d][1,3]dioxole-5-carbaldehyde→2-[(3aR,5R,6aR)-2,2-Dimethylperhydrofuro[2,3-d][1,3]dioxol-5-yl]ethylamine
Ethyl (diethoxyphosphoryl)acetate→3-[(3aR,5S,6aR)-2,2-Dimethylperhydrofuro[2,3-d][1,3]dioxol-5-yl]-2-propenoic acid ethyl ester→3-[(3aR,5R,6aR)-2,2-Dimethylperhydrofuro[2,3-d][1,3]dioxol-5-yl]propionic acid ethyl ester→3-[(3aR,5R,6aR)-2,2-Dimethylperhydrofuro[2,3-d][1,3]dioxol-5-yl]propionamide→1,2-O-Isopropylidene-6-(methoxycarbonylamino)-3,5,6-trideoxy-alpha-D-erythro-hexofuranose→(3aR,5S,6aR)-2,2-Dimethylperhydrofuro[2,3-d][1,3]dioxole-5-carbaldehyde→2-[(3aR,5R,6aR)-2,2-Dimethylperhydrofuro[2,3-d][1,3]dioxol-5-yl]ethylamine
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