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CAS 1129683-83-5
1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-hydroxyphenyl)urea
Codes: SORF-009
Application context (from source-drug indications)
Thyroid cancerSorafenib TosylateHepatocellular carcinomaSorafenib TosylateRenal cell carcinomaSorafenib TosylateAggressive fibromatosisSorafenib TosylateLiver cancerSorafenib TosylateMyeloproliferative neoplasmSorafenib Tosylate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Sorafenib Tosylate | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-chloropicolinoyl chloride→4-aminophenol→4-chloro-3-(trifluoromethyl)aniline→1-(4-hydroxyphenyl)urea→1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(4-hydroxyphenyl)urea
Intermediates available on this site
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