← Back to patent-cliff list
CAS 1143952-11-7
N-Acetyl-3-chloro-L-alanine propyl ester
Codes: Ramipril-045
Application context (from source-drug indications)
HypercholesterolaemiaAtorvastatin Calcium Hydrate/RamiprilHypertensionAtorvastatin Calcium Hydrate/RamiprilHypertensionRamiprilNephropathyRamiprilMyocardial infarctionRamiprilHeart failureRamiprilStrokeRamiprilMitral stenosisRamipril
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Atorvastatin Calcium Hydrate/Ramipril | Tier C — Watch / trade | - |
| Ramipril | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
Propyl L-serinate hydrochloride→N-Acetyl-3-chloro-L-alanine propyl ester→1-(1-Cyclopentenyl)pyrrolidine→N-Acetyl-3-(2-oxocyclopentyl)alanine propyl ester→N-Carbamoyl-3-(2-oxocyclopentyl)alanine→(Methyl 2-(acetylamino)-3-(2-oxocyclopentyl)propanoate)→3-(2-Oxocyclopentyl)-L-alanine→(2S,3aS,6aS)-Octahydrocyclopenta[b]pyrrole-2-carboxylic acid→Benzyl (2S,3aS,6aS)-octahydrocyclopenta[b]pyrrole-2-carboxylate 4-methylbenzenesulfonate→Ethyl (2S)-2-[[(2S)-1-chloro-1-oxopropan-2-yl]amino]-4-phenylbutanoate hydrochloride→N-[(S)-(+)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanine
Propyl L-serinate hydrochloride→N-Acetyl-3-chloro-L-alanine propyl ester→1-(1-Cyclopentenyl)pyrrolidine→N-Acetyl-3-(2-oxocyclopentyl)alanine propyl ester→N-Carbamoyl-3-(2-oxocyclopentyl)alanine→(Methyl 2-(acetylamino)-3-(2-oxocyclopentyl)propanoate)→3-(2-Oxocyclopentyl)-L-alanine→(2S,3aS,6aS)-Octahydrocyclopenta[b]pyrrole-2-carboxylic acid→Benzyl (2S,3aS,6aS)-octahydrocyclopenta[b]pyrrole-2-carboxylate 4-methylbenzenesulfonate→Ethyl (2S)-2-[[(2S)-1-chloro-1-oxopropan-2-yl]amino]-4-phenylbutanoate hydrochloride→N-[(S)-(+)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanine
Intermediates available on this site
No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.