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CAS 115279-73-7
1-(4-aminophenyl)cyclopentanecarbonitrile
Codes: APAT-003
Application context (from source-drug indications)
Breast cancerApatinib MesylateGastric cancerApatinib MesylateNon-small cell lung cancerApatinib MesylateOvarian cancerApatinib MesylatePeritoneal cancerApatinib MesylateEpithelial ovarian cancerApatinib Mesylate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Apatinib Mesylate | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
1-phenylcyclopentanecarbonitrile→1-(4-nitrophenyl)cyclopentanecarbonitrile→1-(4-aminophenyl)cyclopentanecarbonitrile→2-chloronicotinoyl chloride→2-chloro-N-(4-(1-cyanocyclopentyl)phenyl)nicotinamide→pyridin-4-ylmethanamine
Intermediates available on this site
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