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CAS 1190392-22-3
(S)-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-6-carboxylic acid
Codes: VIBE-009
Application context (from source-drug indications)
Overactive bladderVibegronUrinary incontinenceVibegron
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Vibegron | Tier C — Watch / trade | 2031 |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
(4S,5R)-tert-butyl 4-formyl-2,2-dimethyl-5-phenyloxazolidine-3-carboxylate→2-(triphenylphosphoranylidene)acetaldehyde→(4R,5R)-tert-butyl 2,2-dimethyl-4-((E)-3-oxoprop-1-en-1-yl)-5-phenyloxazolidine-3-carboxylate→(4R,5R)-tert-butyl 2,2-dimethyl-4-(3-oxopropyl)-5-phenyloxazolidine-3-carboxylate→(4-nitrobenzyl)triphenylphosphonium bromide→(4R,5R)-tert-butyl 2,2-dimethyl-4-((E)-4-(4-nitrophenyl)but-3-en-1-yl)-5-phenyloxazolidine-3-carboxylate→(2R,5S)-tert-butyl 2-((R)-hydroxy(phenyl)methyl)-5-(4-nitrobenzyl)pyrrolidine-1-carboxylate→(2S,5R)-tert-butyl 2-(4-aminobenzyl)-5-((R)-hydroxy(phenyl)methyl)pyrrolidine-1-carboxylate→(S)-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-6-carboxylic acid→(2R,5S)-tert-butyl 2-((R)-hydroxy(phenyl)methyl)-5-(4-((S)-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-6-carboxamido)benzyl)pyrrolidine-1-carboxylate→(S)-methyl 5-methoxy-3,4-dihydro-2H-pyrrole-2-carboxylate→3-azatricyclo[4.2.1.02,5]non-7-en-4-one→(S)-methyl 4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-6-carboxylate
Intermediates available on this site
Side-by-side comparison of all listed offers on this CAS; price bands are list-price ranges, final price subject to RFQ confirmation.
| Supplier | Product | Price band | MOQ | Lead time | Qualifications | Action |
|---|---|---|---|---|---|---|
| Unibest Taizhou GMP-like Site | (6S)-4,6,7,8-tetrahydro-4-oxo-Pyrrolo[1,2-a]pyriMidine-6-carboxylic acid Pharmaceutical Intermediates | On request | On request | On request | — |
This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.