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CAS 121-71-1
3-Hydroxyacetophenone1-(3-hydroxyphenyl)ethan-1-one1-(3-Hydroxyphenyl)ethanone
Codes: Phenylephrine Hydrochloride-034, RIVAT-009, (I)145089-1-a, (I)145089-2-a, (I)145089-4-a, (I)145089-5-a, (I)145089-6-a, (I)145089-11-a, (I)145089-17-a, (I)145089-20-a, (VI)145089-21-b
Application context (from source-drug indications)
Common coldIbuprofen/Phenylephrine HydrochlorideFeverIbuprofen/Phenylephrine HydrochlorideHeadacheIbuprofen/Phenylephrine HydrochlorideMydriasisPhenylephrine HydrochlorideHypotensionPhenylephrine HydrochlorideCycloplegiaPhenylephrine HydrochlorideSupraventricular tachycardiaPhenylephrine HydrochlorideShockPhenylephrine HydrochlorideIschaemic strokePhenylephrine HydrochlorideAlzheimer's diseaseRivastigmine TartrateDementiaRivastigmine TartrateParkinson's diseaseRivastigmine Tartrate抗胆碱能综合征Rivastigmine Tartrate神经行为学表现Rivastigmine TartrateCognitive impairmentRivastigmine Tartrate
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Ibuprofen/Phenylephrine Hydrochloride | Tier C — Watch / trade | - |
| Phenylephrine Hydrochloride | Tier C — Watch / trade | - |
| Rivastigmine Tartrate | Tier B — Position early | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
3-Hydroxyacetophenone→2-Chloro-1-(3-hydroxyphenyl)ethanone→3-[(1R)-2-Chloro-1-hydroxyethyl]phenol→Methylamine→Phenylephrine
3-Hydroxyacetophenone→2-Chloro-1-(3-hydroxyphenyl)ethanone→3-[(1R)-2-Chloro-1-hydroxyethyl]phenol→Methylamine→Phenylephrine
ethyl(methyl)carbamic chloride→1-(3-hydroxyphenyl)ethan-1-one→(R)-3-(1-hydroxyethyl)phenol→(R)-3-(1-((methylsulfonyl)oxy)ethyl)phenyl methanesulfonate→(S)-3-(1-(dimethylamino)ethyl)phenyl methanesulfonate→(S)-3-(1-(dimethylamino)ethyl)phenol
ethyl(methyl)carbamic chloride→1-(3-hydroxyphenyl)ethan-1-one→3-acetylphenyl ethyl(methyl)carbamate→(S)-3-(1-hydroxyethyl)phenyl ethyl(methyl)carbamate→(R)-3-(1-bromoethyl)phenyl ethyl(methyl)carbamate
1-(3-Hydroxyphenyl)ethanone→3-(1-Aminoethyl)phenol→3-[1-(Dimethylamino)ethyl]phenol→N-Ethyl-N-methylcarbamic chloride→N-Ethyl-N-methylcarbamic acid 3-[1-(N,N-dimethylamino)ethyl]phenyl ester→Formic acid N-methylmethanamine→1-[(1H-Imidazol-1-yl)carbonyl]1H-imidazole→N-Ethyl-N-methylamine→(S)-3-(1-(Dimethylamino)ethyl)phenyl ethyl(methyl)carbamate
1-(3-Hydroxyphenyl)ethanone→1-(3-Methoxyphenyl)ethanone→(1E)-1-(3-Methoxyphenyl)ethanone oxime→1-(3-Methoxyphenyl)ethanamine→1(S)-(3-Methoxyphenyl)ethylamine 2(S)-hydroxy-2-phenylacetate→1(S)-(3-Methoxyphenyl)-N,N-dimethylethylamine→(-)-3-((1S)-1-(Dimethylamino)ethyl)phenol→Potassium 3-[(1S)-1-(dimethylamino)ethyl]phenolate→N-Ethyl-N-methylcarbamic chloride→Ethyl(methyl)carbamic bromide→(S)-3-(1-(Dimethylamino)ethyl)phenyl ethyl(methyl)carbamate→1(R)-(3-Methoxyphenyl)-N,N-dimethylethylamine 2(S)-hydroxy-2-phenylacetate→1(R)-(3-Methoxyphenyl)-N,N-dimethylethylamine→(1R)-1-(3-Methoxyphenyl)ethanol→(1R)-1-(3-Methoxyphenyl)ethyl methanesulfonate→Dimethylamine anhydrous→N-[(1Z)-1-(3-Methoxyphenyl)ethylidene]methanamine→N-Boc-[1(S)-(3-Methoxyphenyl)ethyl]-N-methylamine
1-(3-Hydroxyphenyl)ethanone→3-Acetylphenyl 4-methylbenzenesulfonate→3-[1-(Formylamino)ethyl]phenyl 4-methylbenzenesulfonate→3-(1-Aminoethyl)phenyl 4-methylbenzenesulfonate→3-(1-Aminoethyl)phenol→3-[(1R)-1-Aminoethyl]phenyl 4-methylbenzenesulfonate→3-[(1S)-1-Aminoethyl]phenyl 4-methylbenzenesulfonate→3-[(1S)-1-(Dimethylamino)ethyl]phenyl 4-methylbenzenesulfonate→(-)-3-((1S)-1-(Dimethylamino)ethyl)phenol→N-Ethyl-N-methylcarbamic chloride→(S)-3-(1-(Dimethylamino)ethyl)phenyl ethyl(methyl)carbamate→3-[(1R)-1-[[(E)-Phenylmethylidene]amino]ethyl]phenyl 4-methylbenzenesulfonate→3-(1-[[(E)-Phenylmethylidene]amino]ethyl)phenyl 4-methylbenzenesulfonate
1-(3-Hydroxyphenyl)ethanone→(S)-(-)-1-Phenylethylamine→3-[(1S)-1-[[(1S)-1-Phenylethyl]amino]ethyl]phenol→3-[(1S)-1-[Methyl[(1S)-1-phenylethyl]amino]ethyl]phenol→3-[1(S)-(Methylamino)ethyl]phenol→(-)-3-((1S)-1-(Dimethylamino)ethyl)phenol→N-Ethyl-N-methylamine→(S)-3-(1-(Dimethylamino)ethyl)phenyl ethyl(methyl)carbamate
1-(3-Hydroxyphenyl)ethanone→3-[1(R)-Hydroxyethyl]phenol→3-[(1R)-1-[(Methanesulfonyl)oxy]ethyl]phenyl methanesulfonate→Dimethylamine anhydrous→3-[(1S)-1-(Dimethylamino)ethyl]phenyl methanesulfonate→(-)-3-((1S)-1-(Dimethylamino)ethyl)phenol→N-Ethyl-N-methylcarbamic chloride→(S)-3-(1-(Dimethylamino)ethyl)phenyl ethyl(methyl)carbamate→3-Acetylphenyl ethyl(methyl)carbamate→3-[(1R)-1-Hydroxyethyl]phenyl ethyl(methyl)carbamate→(1R)-1-(3-[[Ethyl(methyl)carbamoyl]oxy]phenyl)ethyl methanesulfonate
1-(3-Hydroxyphenyl)ethanone→Aminomethane→3-[(1E)-N-Methylethanimidoyl]phenol→3-[1-(Methylamino)ethyl]phenol→3-[1(S)-(Methylamino)ethyl]phenol→(-)-3-((1S)-1-(Dimethylamino)ethyl)phenol
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