CAS 121-87-9

1-Amino-2-chloro-4-nitrobenzene

Codes: (II)277894-1-a, (III)277894-3-a

Application context (from source-drug indications)

蛔虫病NiclosamideCOVID-19NiclosamideDiabetic nephropathyNiclosamideAcute myeloid leukaemiaNiclosamideUlcerative colitisNiclosamideUlcerative proctitisNiclosamide

Source drugs (routes using this intermediate)

Drug	Tier	Expiry
Niclosamide	Tier C — Watch / trade	-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

NiclosamideOptimised routesteps: 2total yield: /

1-Amino-4-nitrobenzene→1-Amino-2-chloro-4-nitrobenzene→5-Chloro-2-hydroxybenzoic acid

NiclosamideOptimised routesteps: 2total yield: /

5-Chloro-2-hydroxybenzoic acid→(5-Chloro-2-hydroxyphenyl)(1H-imidazol-1-yl)methanone→1-Amino-2-chloro-4-nitrobenzene

Intermediates available on this site

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