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CAS 122-04-3
4-Nitrobenzoyl chloride4-nitrobenzoyl chloride
Codes: Tetracaine-002, Folic Acid-051, CONI-002
Application context (from source-drug indications)
AnaesthesiaOxymetazoline Hydrochloride/Tetracaine HydrochloridePeriapical periodontitisOxymetazoline Hydrochloride/Tetracaine HydrochlorideDental cariesOxymetazoline Hydrochloride/Tetracaine HydrochlorideEssential hypertensionEnalapril Maleate/Folic AcidHyponatraemiaConivaptan HydrochlorideAcute decompensated heart failureConivaptan HydrochlorideHeart failureConivaptan HydrochlorideLiver diseaseConivaptan HydrochlorideTraumatic brain injuryConivaptan HydrochlorideKidney diseaseConivaptan HydrochlorideAnaesthesiaTetracaine HydrochlorideRetinitis pigmentosaTetracaine HydrochloridePainTetracaine HydrochlorideMegaloblastic anaemiaFolic AcidFolate deficiencyFolic AcidNeural tube defectFolic AcidAnaemiaFolic AcidHot flushesFolic AcidHyperhomocysteinaemiaFolic Acid
Source drugs (routes using this intermediate)
| Drug | Tier | Expiry |
|---|---|---|
| Oxymetazoline Hydrochloride/Tetracaine Hydrochloride | Tier C — Watch / trade | - |
| Enalapril Maleate/Folic Acid | Tier C — Watch / trade | - |
| Conivaptan Hydrochloride | Tier C — Watch / trade | - |
| Tetracaine Hydrochloride | Tier C — Watch / trade | - |
| Folic Acid | Tier C — Watch / trade | - |
Position in synthesis routes (up/downstream chain)
Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.
4-Nitrobenzoic acid→4-Nitrobenzoyl chloride→N,N-Dimethylaminoethanol→2-(Dimethylamino)ethyl 4-nitrobenzoate hydrogen chloride→2-(Dimethylamino)ethyl 4-nitrobenzoate→2-(Dimethylamino)ethyl 4-aminobenzoate hydrogen chloride→4-Aminobenzoic acid 2-(dimethylamino)ethyl ester→Butanal→1-Bromobutane→4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester
4-Nitrobenzoyl chloride→(S)-(+)-Glutamic acid→(2S)-[(4-Nitrobenzoyl)amino]pentanedioic acid→Sodium 1-[[(1S)-1-carboxy-3-carboxylatopropyl]carbamoyl]-4-nitrobenzene→N-(4-Aminobenzoyl)-L-glutamic acid→2,5,6-Triaminopyrimidin-4(5H)-one→2,5,6-Triaminopyrimidin-4-one sulfate→1,1,3-Trichloroacetone
1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one→4-nitrobenzoyl chloride→1-(4-nitrobenzoyl)-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one→1-(4-aminobenzoyl)-1,2,3,4-tetrahydro-5H-benzo[b]azepin-5-one→[1,1'-biphenyl]-2-carboxylic acid→N-(4-(5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamide→acetimidamide hydrochloride→N-(4-(4-bromo-5-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-1-carbonyl)phenyl)-[1,1'-biphenyl]-2-carboxamide
4-Nitrobenzoic acid→4-Nitrobenzoyl chloride→N,N-Dimethylaminoethanol→2-(Dimethylamino)ethyl 4-nitrobenzoate hydrogen chloride→2-(Dimethylamino)ethyl 4-nitrobenzoate→2-(Dimethylamino)ethyl 4-aminobenzoate hydrogen chloride→4-Aminobenzoic acid 2-(dimethylamino)ethyl ester→Butanal→1-Bromobutane→4-(Butylamino)benzoic acid 2-(dimethylamino)ethyl ester
4-Nitrobenzoyl chloride→(S)-(+)-Glutamic acid→(2S)-[(4-Nitrobenzoyl)amino]pentanedioic acid→Sodium 1-[[(1S)-1-carboxy-3-carboxylatopropyl]carbamoyl]-4-nitrobenzene→N-(4-Aminobenzoyl)-L-glutamic acid→2,5,6-Triaminopyrimidin-4(5H)-one→2,5,6-Triaminopyrimidin-4-one sulfate→1,1,3-Trichloroacetone
Intermediates available on this site
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