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CAS 1220040-66-3

Pyridine-4-[11C]carbonitrile

Codes: Isoniazid-018

Application context (from source-drug indications)

Mycobacterium tuberculosis infectionEthambutol Hydrochloride/Rifampicin/IsoniazidPulmonary tuberculosisIsoniazidMycobacterium tuberculosis infectionIsoniazidSystemic lupus erythematosusIsoniazidTonsillitisIsoniazid非复杂性皮肤和皮肤结构感染IsoniazidPneumoniaIsoniazid

Source drugs (routes using this intermediate)

DrugTierExpiry
Ethambutol Hydrochloride/Rifampicin/IsoniazidTier C — Watch / trade-
IsoniazidTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Ethambutol Hydrochloride/Rifampicin/IsoniazidOptimised routesteps: 3total yield: /
4-Iodopyridine→Pyridine-4-[11C]carbonitrile→Hydrazine hydrate→Pyridine-4-[11C]carboximidohydrazide→Pyridine-4-[11C]carbohydrazide
IsoniazidOptimised routesteps: 3total yield: /
4-Iodopyridine→Pyridine-4-[11C]carbonitrile→Hydrazine hydrate→Pyridine-4-[11C]carboximidohydrazide→Pyridine-4-[11C]carbohydrazide

Intermediates available on this site

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