Unibest
← Back to patent-cliff list

CAS 1221157-11-4

methyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate hydrochloride

Codes: BENDAM-009

Application context (from source-drug indications)

B-cell lymphomaBendamustine HydrochlorideNon-Hodgkin lymphomaBendamustine HydrochlorideChronic lymphocytic leukaemiaBendamustine HydrochlorideMantle cell lymphomaBendamustine HydrochlorideLymphomaBendamustine HydrochlorideMultiple myelomaBendamustine Hydrochloride

Source drugs (routes using this intermediate)

DrugTierExpiry
Bendamustine HydrochlorideTier C — Watch / trade-

Position in synthesis routes (up/downstream chain)

Ordered by route registration; left → right is the synthesis direction. The highlighted node is the current CAS; others link to their own profiles.

Bendamustine HydrochlorideProcess routesteps: 5total yield: 626 g
2,4-dinitroaniline→methyl 5-chloro-5-oxopentanoate→methyl 5-((2,4-dinitrophenyl)amino)-5-oxopentanoate→methyl 5-((2,4-dinitrophenyl)(methyl)amino)-5-oxopentanoate→methyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate hydrochloride→methyl 4-(5-(bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate

Intermediates available on this site

No listed intermediates for this target yet — send an RFQ directly and it will enter our matching pool.

This is a CAS-level registry record: registrations across routes are merged. Supplier offers and buyer demands will be matched on this CAS as the primary key.